How best to assess the quality of life in long-term survivors after surgery for NSCLC? Comparison between clinical predictors and questionnaire scores

Silvia Sterzi, Alfredo Cesario, Giacomo Cusumano, Giuseppe Corbo, Filippo Lococo, Barbara Biasotti, Luisa Maria Lapenna, Giovanni Magrone, Valentina Dall'Armi, Elisa Meacci, Venanzio Porziella, Stefano Bonassi, Stefano Margaritora, Pierluigi Granone

Research output: Contribution to journalArticle

Abstract

Background: The determinants and predictors of QOL in lung cancer survivors who have received surgery remain defined vaguely and still debated. We evaluate clinical, surgical, and pulmonary function characteristics as predictors of QOL in long-term lung cancer survivors who received surgery. Methods: Quality of life was evaluated 5 years after surgery in 67 lung cancer patients using the European Organization for Research and Treatment of Cancer (EORTC) QOL Core Questionnaire, its lung cancer-specific module QLQ LC-13, and the Hospital Anxiety and Depression Scale questionnaire. Preoperative clinical, surgical, and pathologic data were matched with the questionnaire scores. Results: Sex was associated with role functioning and symptoms, with males more often reporting fatigue and pain, appetite loss, coughing, and hemoptysis (P 1) and forced vital capacity (FVC) were significantly (P 1 and FVC were associated with lower global function and a greater severity of specific and nonspecific symptoms (P

Original languageEnglish
Pages (from-to)78-87
Number of pages10
JournalClinical Lung Cancer
Volume14
Issue number1
DOIs
Publication statusPublished - Jan 2013

Keywords

  • Long-term lung cancer survivors
  • Lung carcinoma
  • Pulmonary function
  • QOL
  • Questionnaire

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Pulmonary and Respiratory Medicine

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    Sterzi, S., Cesario, A., Cusumano, G., Corbo, G., Lococo, F., Biasotti, B., Lapenna, L. M., Magrone, G., Dall'Armi, V., Meacci, E., Porziella, V., Bonassi, S., Margaritora, S., & Granone, P. (2013). How best to assess the quality of life in long-term survivors after surgery for NSCLC? Comparison between clinical predictors and questionnaire scores. Clinical Lung Cancer, 14(1), 78-87. https://doi.org/10.1016/j.cllc.2012.04.002