How cartilage status can be related to joint loads in anterior cruciate ligament reconstruction: a preliminary analysis including MRI t2 mapping and joint biomechanics

Giorgio Cassiolas, Matteo Berni, Gregorio Marchiori, Marco Bontempi, L Bragonzoni, Giordano Valente, Alberto Grassi, Stefano Zaffagnini, Andrea Visani, Nicola Francesco Lopomo

Research output: Contribution to journalArticlepeer-review

Abstract

The knee is the largest and most complex joint in the human body. Traumatic events, such as anterior cruciate ligament (ACL) tear, can lead to an alteration of joint tissues homeostasis. Literature reports an evident correlation between abnormal joint biomechanics and the status of articular tissues. These alterations, due to a sub-optimal ACL reconstruction, may result in an increasing risk of developing degenerative pathologies, such as osteoarthritis. Thus, the identification of the optimal surgical technique is a highly demanding issue in ACL reconstruction. The aim of this study was to analyze the correlation between joint cartilage conditions and knee biomechanics in ACL reconstructions, by integrating MRI T2 mapping investigations, radiostereophotogrammetry-based gait analysis and subject-specific musculoskeletal modelling.

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalJournal of Biological Regulators and Homeostatic Agents
Volume32
Issue number6 Suppl. 1
Publication statusPublished - Dec 2018

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