TY - JOUR
T1 - How cartilage status can be related to joint loads in anterior cruciate ligament reconstruction: a preliminary analysis including MRI t2 mapping and joint biomechanics
AU - Cassiolas, Giorgio
AU - Berni, Matteo
AU - Marchiori, Gregorio
AU - Bontempi, Marco
AU - Bragonzoni, L
AU - Valente, Giordano
AU - Grassi, Alberto
AU - Zaffagnini, Stefano
AU - Visani, Andrea
AU - Lopomo, Nicola Francesco
PY - 2018/12
Y1 - 2018/12
N2 - The knee is the largest and most complex joint in the human body. Traumatic events, such as anterior cruciate ligament (ACL) tear, can lead to an alteration of joint tissues homeostasis. Literature reports an evident correlation between abnormal joint biomechanics and the status of articular tissues. These alterations, due to a sub-optimal ACL reconstruction, may result in an increasing risk of developing degenerative pathologies, such as osteoarthritis. Thus, the identification of the optimal surgical technique is a highly demanding issue in ACL reconstruction. The aim of this study was to analyze the correlation between joint cartilage conditions and knee biomechanics in ACL reconstructions, by integrating MRI T2 mapping investigations, radiostereophotogrammetry-based gait analysis and subject-specific musculoskeletal modelling.
AB - The knee is the largest and most complex joint in the human body. Traumatic events, such as anterior cruciate ligament (ACL) tear, can lead to an alteration of joint tissues homeostasis. Literature reports an evident correlation between abnormal joint biomechanics and the status of articular tissues. These alterations, due to a sub-optimal ACL reconstruction, may result in an increasing risk of developing degenerative pathologies, such as osteoarthritis. Thus, the identification of the optimal surgical technique is a highly demanding issue in ACL reconstruction. The aim of this study was to analyze the correlation between joint cartilage conditions and knee biomechanics in ACL reconstructions, by integrating MRI T2 mapping investigations, radiostereophotogrammetry-based gait analysis and subject-specific musculoskeletal modelling.
UR - https://www.ncbi.nlm.nih.gov/pubmed/?term=How+cartilage+status+can+be+related+to+joint+loads+in+anterior+cruciate+ligament+reconstruction%3A+a+preliminary+analysis+including+MRI+t2+mapping+and+joint+biomechanics
M3 - Article
C2 - 30644279
VL - 32
SP - 35
EP - 40
JO - Journal of Biological Regulators and Homeostatic Agents
JF - Journal of Biological Regulators and Homeostatic Agents
SN - 0393-974X
IS - 6 Suppl. 1
ER -