How complete is full thickness disc resection of bowel endometriotic lesions? A prospective surgical and histological study

V. Remorgida, N. Ragni, S. Ferrero, P. Anserini, P. Torelli, E. Fulcheri

Research output: Contribution to journalArticle

Abstract

Background: This study aims to evaluate the completeness of full thickness disc resection in the treatment of deep endometriotic bowel lesions. Methods: This study comprised 16 women with bowel endometriotic lesions requiring segmental resection. For the purpose of the study, before intestinal resection, nodulectomy was performed. The presence of endometriotic infiltration in direct continuity with the removed nodule and the presence of fibrosis in the area surrounding the nodule were histologically evaluated. Results: In seven out of 16 cases (43.8%; 95% CI, 19.8-70.1), endometriosis was found in the bowel wall adjacent to the site of nodulectomy; the infiltration was visible in the muscular layer in all cases. In cases of incomplete nodulectomy, the muscular layer of the bowel segment surrounding the endometriotic nodule contained limited or no fibrosis. Conclusions: Full thickness discresection is not complete in ≥40% of women with bowel endometriosis. Our finding that fibrosis in the muscular layer, the main landmark during surgical resection, does not always surround bowel endometriotic lesions might explain why incomplete resection may occur.

Original languageEnglish
Pages (from-to)2317-2320
Number of pages4
JournalHuman Reproduction
Volume20
Issue number8
DOIs
Publication statusPublished - Aug 2005

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Fibrosis
Endometriosis
Therapeutics

Keywords

  • Bowel endometriosis
  • Bowel resection
  • Fibrosis
  • Full thickness disc resection
  • Laparoscopy

ASJC Scopus subject areas

  • Developmental Biology
  • Physiology
  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

How complete is full thickness disc resection of bowel endometriotic lesions? A prospective surgical and histological study. / Remorgida, V.; Ragni, N.; Ferrero, S.; Anserini, P.; Torelli, P.; Fulcheri, E.

In: Human Reproduction, Vol. 20, No. 8, 08.2005, p. 2317-2320.

Research output: Contribution to journalArticle

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AU - Ragni, N.

AU - Ferrero, S.

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AU - Torelli, P.

AU - Fulcheri, E.

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N2 - Background: This study aims to evaluate the completeness of full thickness disc resection in the treatment of deep endometriotic bowel lesions. Methods: This study comprised 16 women with bowel endometriotic lesions requiring segmental resection. For the purpose of the study, before intestinal resection, nodulectomy was performed. The presence of endometriotic infiltration in direct continuity with the removed nodule and the presence of fibrosis in the area surrounding the nodule were histologically evaluated. Results: In seven out of 16 cases (43.8%; 95% CI, 19.8-70.1), endometriosis was found in the bowel wall adjacent to the site of nodulectomy; the infiltration was visible in the muscular layer in all cases. In cases of incomplete nodulectomy, the muscular layer of the bowel segment surrounding the endometriotic nodule contained limited or no fibrosis. Conclusions: Full thickness discresection is not complete in ≥40% of women with bowel endometriosis. Our finding that fibrosis in the muscular layer, the main landmark during surgical resection, does not always surround bowel endometriotic lesions might explain why incomplete resection may occur.

AB - Background: This study aims to evaluate the completeness of full thickness disc resection in the treatment of deep endometriotic bowel lesions. Methods: This study comprised 16 women with bowel endometriotic lesions requiring segmental resection. For the purpose of the study, before intestinal resection, nodulectomy was performed. The presence of endometriotic infiltration in direct continuity with the removed nodule and the presence of fibrosis in the area surrounding the nodule were histologically evaluated. Results: In seven out of 16 cases (43.8%; 95% CI, 19.8-70.1), endometriosis was found in the bowel wall adjacent to the site of nodulectomy; the infiltration was visible in the muscular layer in all cases. In cases of incomplete nodulectomy, the muscular layer of the bowel segment surrounding the endometriotic nodule contained limited or no fibrosis. Conclusions: Full thickness discresection is not complete in ≥40% of women with bowel endometriosis. Our finding that fibrosis in the muscular layer, the main landmark during surgical resection, does not always surround bowel endometriotic lesions might explain why incomplete resection may occur.

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