How frequent and how early does the neurological involvement in HIV-positive children occur? - Preliminary results of a prospective study

A. M. Laverda; P. Cogo; A. Condini; C. Cattelan; C. Giaquinto; S. Cozzani; E. Ruga; F. Viero; A. De Rossi; A. Del Mistro; L. Chieco Bianchi; F. Zacchello

doi:10.1007/BF00302228

How frequent and how early does the neurological involvement in HIV-positive children occur? - Preliminary results of a prospective study

A. M. Laverda, P. Cogo, A. Condini, C. Cattelan, C. Giaquinto, S. Cozzani, E. Ruga, F. Viero, A. De Rossi, A. Del Mistro, L. Chieco Bianchi, F. Zacchello

Research output: Contribution to journal › Article › peer-review

Abstract

To study the natural history of the neurological involvement in pediatric human immunodeficiency virus (HIV) infection, 77 children born to seropositive mothers have been followed up since birth. The median follow-up time has been 17.5 months. Fourteen children were classified as infected, 34 as not infected, and 21 as indeterminable. Only two children with full-blown acute immune deficiency syndrome had severe neurological manifestations. "Soft" neurological signs were found in six infected, and ten non-infected children (χ², P0.05). These data suggest that neurological and developmental abnormalities do not occur early in the course of vertical HIV infection and that they are associated with severe immunodeficiency.

Original language	English
Pages (from-to)	406-408
Number of pages	3
Journal	Child's Nervous System
Volume	6
Issue number	7
DOIs	https://doi.org/10.1007/BF00302228
Publication status	Published - Nov 1990

Keywords

Children
HIV infection
Neurological manifestation

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Clinical Neurology

Access to Document

10.1007/BF00302228

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Laverda, A. M., Cogo, P., Condini, A., Cattelan, C., Giaquinto, C., Cozzani, S., Ruga, E., Viero, F., De Rossi, A., Del Mistro, A., Chieco Bianchi, L., & Zacchello, F. (1990). How frequent and how early does the neurological involvement in HIV-positive children occur? - Preliminary results of a prospective study. Child's Nervous System, 6(7), 406-408. https://doi.org/10.1007/BF00302228

How frequent and how early does the neurological involvement in HIV-positive children occur? - Preliminary results of a prospective study. / Laverda, A. M.; Cogo, P.; Condini, A.; Cattelan, C.; Giaquinto, C.; Cozzani, S.; Ruga, E.; Viero, F.; De Rossi, A.; Del Mistro, A.; Chieco Bianchi, L.; Zacchello, F.

In: Child's Nervous System, Vol. 6, No. 7, 11.1990, p. 406-408.

Research output: Contribution to journal › Article › peer-review

Laverda, AM, Cogo, P, Condini, A, Cattelan, C, Giaquinto, C, Cozzani, S, Ruga, E, Viero, F, De Rossi, A , Del Mistro, A, Chieco Bianchi, L & Zacchello, F 1990, 'How frequent and how early does the neurological involvement in HIV-positive children occur? - Preliminary results of a prospective study', Child's Nervous System, vol. 6, no. 7, pp. 406-408. https://doi.org/10.1007/BF00302228

Laverda, A. M. ; Cogo, P. ; Condini, A. ; Cattelan, C. ; Giaquinto, C. ; Cozzani, S. ; Ruga, E. ; Viero, F. ; De Rossi, A. ; Del Mistro, A. ; Chieco Bianchi, L. ; Zacchello, F. / How frequent and how early does the neurological involvement in HIV-positive children occur? - Preliminary results of a prospective study. In: Child's Nervous System. 1990 ; Vol. 6, No. 7. pp. 406-408.

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