How I manage medical complications of b-thalassemia in adults

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The complex pathophysiology in b-thalassemia can translate to multiple morbidities that affect every organ system. Improved survival due to advances in management means that patients are exposed to the harmful effects of ineffective erythropoiesis, anemia, and iron overload for a longer duration, and we started seeing new or more frequent complications in adult compared with younger patients. In this article, we highlight particular aspects of managing adult patients with b-thalassemia, using our own experience in treating such patients. We cover both transfusion-dependent and nontransfusion-dependent forms of the disease and tackle specific morbidities of highest interest.

Original languageEnglish
Pages (from-to)1781-1791
Number of pages11
JournalBlood
Volume132
Issue number17
DOIs
Publication statusPublished - Oct 25 2018

Fingerprint

Thalassemia
Iron
Morbidity
Iron Overload
Erythropoiesis
Anemia
Survival

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

Cite this

How I manage medical complications of b-thalassemia in adults. / Taher, Ali T.; Cappellini, Maria Domenica.

In: Blood, Vol. 132, No. 17, 25.10.2018, p. 1781-1791.

Research output: Contribution to journalArticle

Taher, Ali T. ; Cappellini, Maria Domenica. / How I manage medical complications of b-thalassemia in adults. In: Blood. 2018 ; Vol. 132, No. 17. pp. 1781-1791.
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