How I treat rare venous thromboses

Ida Martinelli, Massimo Franchini, Pier Mannuccio Mannucci

Research output: Contribution to journalArticlepeer-review

Abstract

Venous thromboembolism may involve venous sites other than the lower limbs, such as cerebral, splanchnic, and upper limb veins. Although uncommon, these thromboses may be clinically severe and challenging for caregivers. In this review, the main pathogenic, clinical, and therapeutic features of thromboses in rare venous sites are discussed. Even though there was a lot of recent progress in understanding the mechanistic role of inherited and acquired thrombophilia and of the interactions between different risk factors, the optimal management of these patients is still unsettled, being currently based on the consensus ofexperts due to the lack of randomized trials. The implementation of large interdisciplinary registries is a necessary weapon to optimize the treatment of rare venous diseases.

Original languageEnglish
Pages (from-to)4818-4823
Number of pages6
JournalBlood
Volume112
Issue number13
DOIs
Publication statusPublished - Dec 15 2008

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Immunology
  • Hematology

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