TY - JOUR
T1 - How I treat rare venous thromboses
AU - Martinelli, Ida
AU - Franchini, Massimo
AU - Mannucci, Pier Mannuccio
PY - 2008/12/15
Y1 - 2008/12/15
N2 - Venous thromboembolism may involve venous sites other than the lower limbs, such as cerebral, splanchnic, and upper limb veins. Although uncommon, these thromboses may be clinically severe and challenging for caregivers. In this review, the main pathogenic, clinical, and therapeutic features of thromboses in rare venous sites are discussed. Even though there was a lot of recent progress in understanding the mechanistic role of inherited and acquired thrombophilia and of the interactions between different risk factors, the optimal management of these patients is still unsettled, being currently based on the consensus ofexperts due to the lack of randomized trials. The implementation of large interdisciplinary registries is a necessary weapon to optimize the treatment of rare venous diseases.
AB - Venous thromboembolism may involve venous sites other than the lower limbs, such as cerebral, splanchnic, and upper limb veins. Although uncommon, these thromboses may be clinically severe and challenging for caregivers. In this review, the main pathogenic, clinical, and therapeutic features of thromboses in rare venous sites are discussed. Even though there was a lot of recent progress in understanding the mechanistic role of inherited and acquired thrombophilia and of the interactions between different risk factors, the optimal management of these patients is still unsettled, being currently based on the consensus ofexperts due to the lack of randomized trials. The implementation of large interdisciplinary registries is a necessary weapon to optimize the treatment of rare venous diseases.
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U2 - 10.1182/blood-2008-07-165969
DO - 10.1182/blood-2008-07-165969
M3 - Article
C2 - 18805965
AN - SCOPUS:58149386405
VL - 112
SP - 4818
EP - 4823
JO - Blood
JF - Blood
SN - 0006-4971
IS - 13
ER -