How increased pertussis vaccination coverage is changing the epidemiology of pertussis in Italy

M. Cristina Rota, Fortunato D'Ancona, Marco Massari, Donatella Mandolini, Anna Giammanco, Patrizia Carbonari, Stefania Salmaso, Marta Luisa Ciofi Degli Atti, S. Barbuti, M. C. Berlinghieri, W. Caraccio, E. Ciotoli, L. Cosentino, E. Del Prete, A. Favero, A. Focà, M. Fringuelli, C. Germinario, A. Goglio, S. GrandessoM. Greco, F. Leoncini, G. Maistri, D. Marchetti, P. Martelli, P. Montanera, A. Mundo, G. Obino, S. Oliva, S. Pegoretti, V. Perani, P. Quaranta, G. Riario Sforza, G. Santini, L. Simula, L. Titone, M. Tronci

Research output: Contribution to journalArticlepeer-review

Abstract

The epidemiology of pertussis in Italy is described by using data from the statutory notification system and from seroepidemiology studies. Starting from the 1990s, the incidence of pertussis in Italy has shown a sharp decline and is now at the lowest level ever reached. During this time period vaccination coverage has increased from 88% in 1998 to 95% in 2003. In 1996-97, the prevalence of subjects with levels of IgG antibodies against PT greater than 2 EU/ml was 77.6%. The increase in vaccination coverage will probably change the pattern of disease transmission and increase the number of susceptible adults, unless administration of booster doses to adolescents and adults is considered.

Original languageEnglish
Pages (from-to)5299-5305
Number of pages7
JournalVaccine
Volume23
Issue number46-47
DOIs
Publication statusPublished - Nov 16 2005

Keywords

  • Italy
  • Pertussis
  • Seroepidemiology
  • Vaccination coverage

ASJC Scopus subject areas

  • Immunology
  • Microbiology
  • Virology
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • veterinary(all)

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