Abstract
Summary: Electrical status epilepticus in sleep is an age-dependent syndrome with the characteristic pattern of continuous spike and waves during non-rapid eye movement sleep. Most children can present developmental deterioration. The demonstration of the EEG pattern has to rely on all night long EEG recordings. A comprehensive neuropsychologic evaluation with periodic reassessment should be performed. For the idiopathic forms of electrical status epilepticus in sleep, clobazam could be considered as the first-line therapy; in the other cases, corticosteroids, in particular intravenous methylprednisolone pulse therapy, remain the most effective and should be considered the therapy of choice.
Original language | English |
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Pages (from-to) | 3-9 |
Number of pages | 7 |
Journal | Journal of Clinical Neurophysiology |
Volume | 33 |
Issue number | 1 |
DOIs | |
Publication status | Published - Feb 1 2016 |
Keywords
- Clobazam
- E-SES
- Methylprednisolone
- Neuropsychologic assessment
- Spike-wave index
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
- Physiology
- Physiology (medical)