TY - JOUR
T1 - How to read a pathology report of a bone tumor
AU - Guinebretière, Jean Marc
AU - Kreshak, Jennifer
AU - Suciu, Voichita
AU - De Maulmont, Charles
AU - Mascard, Eric
AU - Missenard, Gilles
AU - Larousserie, Frederique
AU - Vanel, Daniel
PY - 2013/12
Y1 - 2013/12
N2 - The interpretation of a biopsy specimen involving bone is one of the most challenging feats for a pathol-ogist, as it is often difficult to distinguish between benign or reactive lesions and malignant tumors onmicroscopic analysis. Therefore, correlation with the clinical data and imaging is essential and some-times it is only the evolution of certain characteristics over time or information garnered from molecularanalysis that can provide an accurate diagnosis. The pathology report is critical in that it will define sub-sequent patient management; its wording must precisely reflect those elements that are known withcertainty and those that are diagnostic hypotheses. It must be systematic, thorough, and complete andshould not be limited to a simple conclusion. The pathologist must first ensure the completeness andcorrect transcription of the information provided with the specimen, then describe and analyze the his-tology as well as the quality and representative nature of the sample (as they relate to the radiographicfindings and preliminary/final diagnoses), and finally, compare what is seen under the microscope withthe assessment made by the radiologist and/or surgeon.This analysis helps to identify difficult cases requiring further consultation between the radiologist andpathologist.There are multiple reasons for misinterpretation of a pathology report. An important and largelyunderestimated reason is varied interpretations of terms used by the pathologist. Standardized pathol-ogy reports with concise phrases as well as multidisciplinary meetings may limit errors and should beencouraged for optimal diagnostic accuracy
AB - The interpretation of a biopsy specimen involving bone is one of the most challenging feats for a pathol-ogist, as it is often difficult to distinguish between benign or reactive lesions and malignant tumors onmicroscopic analysis. Therefore, correlation with the clinical data and imaging is essential and some-times it is only the evolution of certain characteristics over time or information garnered from molecularanalysis that can provide an accurate diagnosis. The pathology report is critical in that it will define sub-sequent patient management; its wording must precisely reflect those elements that are known withcertainty and those that are diagnostic hypotheses. It must be systematic, thorough, and complete andshould not be limited to a simple conclusion. The pathologist must first ensure the completeness andcorrect transcription of the information provided with the specimen, then describe and analyze the his-tology as well as the quality and representative nature of the sample (as they relate to the radiographicfindings and preliminary/final diagnoses), and finally, compare what is seen under the microscope withthe assessment made by the radiologist and/or surgeon.This analysis helps to identify difficult cases requiring further consultation between the radiologist andpathologist.There are multiple reasons for misinterpretation of a pathology report. An important and largelyunderestimated reason is varied interpretations of terms used by the pathologist. Standardized pathol-ogy reports with concise phrases as well as multidisciplinary meetings may limit errors and should beencouraged for optimal diagnostic accuracy
KW - Bone lesions
KW - Bone tumors
KW - Core needle biopsy
KW - Diagnosis
KW - Histology report
KW - Large core needle biopsy
KW - Pathology
KW - Surgical biopsy
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U2 - 10.1016/j.ejrad.2011.11.036
DO - 10.1016/j.ejrad.2011.11.036
M3 - Article
C2 - 22225961
AN - SCOPUS:84890793805
VL - 82
SP - 2092
EP - 2099
JO - European Journal of Radiology
JF - European Journal of Radiology
SN - 0720-048X
IS - 12
ER -