HPV and Chlamydia trachomatis co-detection in young asymptomatic women from high incidence area for cervical cancer

Serena Bellaminutti, Silva Seraceni, Francesco de Seta, Tarik Gheit, Massimo Tommasino, Manola Comar

Research output: Contribution to journalArticle

Abstract

Chlamydia trachomatis causing chronic inflammatory diseases has investigated as possible human papillomavirus (HPV) cofactor in cervical cancer. The aim of this study is to evaluate the prevalence of Chlamydia trachomatis and HPV co-infection in different cohorts of asymptomatic women from a Northern Italy area at high incidence for cervical cancer. Cervical samples from 441 females were collected from Cervical Cancer Screening Program, Sexually Transmitted Infectious and Assisted Reproductive Technology centres. HPV and Chlamydia trachomatis were detected simultaneously and genotyped using a highly sensitive bead based assay. The overall prevalence of Chlamydia trachomatis was estimated 9.7%, in contrast with the reported national data of 2.3%, and co-infection with HPV was diagnosed in the 17% of the samples. In females ≤25 years of age, the infection reached a peak of 22% and co-infection with HPV of 45.8% (P

Original languageEnglish
Pages (from-to)1920-1925
Number of pages6
JournalJournal of Medical Virology
Volume86
Issue number11
DOIs
Publication statusPublished - 2014

Keywords

  • Cancer co-factors
  • Cervical lesions
  • Chlamydia trachomatis
  • Chlamydia trachomatis screening
  • Human papillomavirus

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases
  • Medicine(all)

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