Human brain oscillatory activity phase-locked to painful electrical stimulations: A multi-channel EEG study

Claudio Babiloni, Fabio Babiloni, Filippo Carducci, Febo Cincotti, Fabrizio Rosciarelli, Lars Arendt-Nielsen, Andrew C N Chen, Paolo Maria Rossini

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

The main aims of this study were 1) a fine spatial analysis of electroencephalographic (EEG) oscillations after galvanic painful stimulation (nonpainful stimulation as a reference) and 2) a comparative evaluation of phase- and nonphase-locked component of these EEG oscillations. Preliminary surface Laplacian transformation of EEG data (31 channels) reduced head volume conductor effects. EEG phase values were computed by FFT analysis and the statistical evaluation of these values was performed by Rayleigh test (P <0.05). About 50% of the EEG single trials presented statistically the same FFT phase value of the evoked EEG oscillations (phase-locked single trials), indicating a preponderant phase-locked compared to nonphase-locked component. The remaining single trials showed random FFT phase values (nonphase-locked single trials), indicating a preponderant nonphase-locked compared to phase-locked component. Compared to nonpainful stimulation, painful stimulation increased phase-locked theta to gamma band responses in the contralateral hemisphere and decreased the phase-locked beta band response in the ipsilateral hemisphere. Furthermore, nonphase-locked alpha band response decreased in the ipsilateral fronto-central area. In conclusion, both decreased and increased EEG oscillatory responses to galvanic painful stimulation would occur in parallel in different cortical regions and in the phase- and nonphase-locked EEG data sets. This enriches the actual debate on the mapping of event-related oscillatory activity of human brain.

Original languageEnglish
Pages (from-to)112-123
Number of pages12
JournalHuman Brain Mapping
Volume15
Issue number2
DOIs
Publication statusPublished - 2002

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Electric Stimulation
Spatial Analysis
Brain
Human Activities
Head
Datasets

Keywords

  • Brain mapping
  • Human pain
  • Median-nerve somatosensory-evoked potentials
  • Phase-locked EEG rhythms
  • Surface Laplacian

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)
  • Radiological and Ultrasound Technology

Cite this

Human brain oscillatory activity phase-locked to painful electrical stimulations : A multi-channel EEG study. / Babiloni, Claudio; Babiloni, Fabio; Carducci, Filippo; Cincotti, Febo; Rosciarelli, Fabrizio; Arendt-Nielsen, Lars; Chen, Andrew C N; Rossini, Paolo Maria.

In: Human Brain Mapping, Vol. 15, No. 2, 2002, p. 112-123.

Research output: Contribution to journalArticle

Babiloni, C, Babiloni, F, Carducci, F, Cincotti, F, Rosciarelli, F, Arendt-Nielsen, L, Chen, ACN & Rossini, PM 2002, 'Human brain oscillatory activity phase-locked to painful electrical stimulations: A multi-channel EEG study', Human Brain Mapping, vol. 15, no. 2, pp. 112-123. https://doi.org/10.1002/hbm.10013
Babiloni, Claudio ; Babiloni, Fabio ; Carducci, Filippo ; Cincotti, Febo ; Rosciarelli, Fabrizio ; Arendt-Nielsen, Lars ; Chen, Andrew C N ; Rossini, Paolo Maria. / Human brain oscillatory activity phase-locked to painful electrical stimulations : A multi-channel EEG study. In: Human Brain Mapping. 2002 ; Vol. 15, No. 2. pp. 112-123.
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