We report here the isolation and characterization of a novel human elongation factor-1 β (EF-1β) gene by cDNA selection from YAC mapping on chromosome 5q12-q14. This gene is specifically transcribed in fetal brain and in skeletal muscle and is characterized by a complete sequence homology with previously described EF-1β cDNAs. We also assigned the loci for three other EF-1β isoforms, to human chromosomes 2, 15 and X. The multiple chromosomal assignments of EF-1β loci demontrates the genetic heterogeneity of human EF-1β peptides.
|Number of pages||9|
|Journal||Biochemical and Biophysical Research Communications|
|Publication status||Published - Nov 30 1993|
ASJC Scopus subject areas
- Molecular Biology