Human enteric coronaviruses: Antigenic relatedness to human coronavirus oc43 and possible etiologic role in viral gastroenteritis

Giuseppe Gerna, Nilda Passarani, Massimo Battaglia, Elio G. Rondanelli

Research output: Contribution to journalArticle

Abstract

In a group of infants with acute nonbacterial gastroenteritis, examination of paired sera for antibody to human coronavirus (HCV) OC43 and neonatal calf diarrhea coronavirus showed a peculiar pattern of serological response, restricted only to HCV OC43 surface antigens, in a significantly higher proportion than among age-matched controls. In another group of infants and young children with acute nonbacterial gastroenteritis, fecal excretion of coronavirus-like particles was detected by electron microscopy in 34 (16.3%) of 208 patients as compared with three (1.6%) of 182 controls (P

Original languageEnglish
Pages (from-to)796-803
Number of pages8
JournalJournal of Infectious Diseases
Volume151
Issue number5
DOIs
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Infectious Diseases
  • Immunology and Allergy
  • Immunology
  • Public Health, Environmental and Occupational Health

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