Human eosinophils and parasitic diseases: light and electron microscopy evidence of interaction with sheep erythrocyte

C. de Simone, G. Donelli, D. Meli, F. Rosati, F. Sorice

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The aim of this study was to investigate the possible formation of spontaneous rosettes between human eosinophils and sheep erythrocytes. In patients with parasitic diseases a percentage of 15.7 ± 6 (range 6-23%), eosinophils were able to form rosettes. Each rosette showed as few as 4 to 8 erythrocytes attached per eosinophil. Two types of interaction were observed at the electron microscope: point attachments and large surface contacts. In patients with non-parasite induced eosinophilia the formation of rosettes is decidedly below the above-mentioned percentage (

Original languageEnglish
Pages (from-to)247-253
Number of pages7
JournalClinical and Experimental Immunology
Issue number1
Publication statusPublished - 1980


ASJC Scopus subject areas

  • Immunology

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