TY - JOUR
T1 - Human infections due to Schizophyllum commune
T2 - Case report and review of the literature
AU - Cavanna, C.
AU - Pagella, F.
AU - Esposto, M. C.
AU - Tamarozzi, F.
AU - Clemente, L.
AU - Marone, P.
AU - Matti, E.
AU - Lallitto, F.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Schizophyllum commune is an environmental basidiomycetous fungus, causing occasional, predominantly respiratory, infections in humans. Although S. commune is considered an emerging pathogen, some authors pointed out the possibility that the increase in the diagnosed cases may be also due to recent advances in diagnostic technologies now allowing a more prompt and precise identification at the species level. Here we describe the first Italian case of chronic non-invasive fungal rhinosinusitis due to S. commune in an immunocompetent subject and update the literature review on S. commune sinusitis published between 2012–2019. A timely diagnosis is important to avoid local and systemic complications due to infection with this fungus. In our case, prompt identification at species level was only possible with the use of MALDI-TOF mass spectrometry and confirmed by sequence analysis of ribosomal DNA ITS regions, due to the difficulty in achieving a correct and rapid identification using routine morphological analysis.
AB - Schizophyllum commune is an environmental basidiomycetous fungus, causing occasional, predominantly respiratory, infections in humans. Although S. commune is considered an emerging pathogen, some authors pointed out the possibility that the increase in the diagnosed cases may be also due to recent advances in diagnostic technologies now allowing a more prompt and precise identification at the species level. Here we describe the first Italian case of chronic non-invasive fungal rhinosinusitis due to S. commune in an immunocompetent subject and update the literature review on S. commune sinusitis published between 2012–2019. A timely diagnosis is important to avoid local and systemic complications due to infection with this fungus. In our case, prompt identification at species level was only possible with the use of MALDI-TOF mass spectrometry and confirmed by sequence analysis of ribosomal DNA ITS regions, due to the difficulty in achieving a correct and rapid identification using routine morphological analysis.
KW - DNA sequencing
KW - Fiberoptic endoscopic sinus surgery (FESS)
KW - Fungal rhinosinusitis
KW - Fungus ball
KW - MALDI-TOF MS
KW - Schizophyllum commune
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U2 - 10.1016/j.mycmed.2019.100897
DO - 10.1016/j.mycmed.2019.100897
M3 - Article
AN - SCOPUS:85072292337
JO - Journal de Mycologie Medicale
JF - Journal de Mycologie Medicale
SN - 1156-5233
M1 - 100897
ER -