Human leukocyte antigen crossmatch testing is important for liver retransplantation

Angeline Goh, Mario Scalamogna, Tullia De Feo, Francesca Poli, Paul I. Terasaki

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Although human leukocyte antigen (HLA) crossmatching is often thought to be unnecessary for liver transplants (LTs), we provide evidence that for retransplants, it is essential. Sera from 139 retransplant patients who had received livers from deceased donors were retrospectively analyzed with single antigen beads on a Luminex platform for HLA antibodies. Each patient received at least 2 transplants and was followed up for at least 6 months from the second LT, which was deemed to have failed if the patient had a third LT or died. Second LT survival was calculated from the date of the second LT to the date of the third LT or death. Our study cohort consisted of 118 adult patients (≥18 years old) as well as 21 pediatric patients (

Original languageEnglish
Pages (from-to)308-313
Number of pages6
JournalLiver Transplantation
Volume16
Issue number3
DOIs
Publication statusPublished - Mar 2010

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HLA Antigens
Transplants
Liver
Cohort Studies
Tissue Donors
Pediatrics
Antigens
Survival
Antibodies
Serum

ASJC Scopus subject areas

  • Surgery
  • Transplantation
  • Hepatology

Cite this

Human leukocyte antigen crossmatch testing is important for liver retransplantation. / Goh, Angeline; Scalamogna, Mario; De Feo, Tullia; Poli, Francesca; Terasaki, Paul I.

In: Liver Transplantation, Vol. 16, No. 3, 03.2010, p. 308-313.

Research output: Contribution to journalArticle

Goh, Angeline ; Scalamogna, Mario ; De Feo, Tullia ; Poli, Francesca ; Terasaki, Paul I. / Human leukocyte antigen crossmatch testing is important for liver retransplantation. In: Liver Transplantation. 2010 ; Vol. 16, No. 3. pp. 308-313.
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