Human melanoma-associated antigens identified with monoclonal antibodies - Structural profile and potential usefulness in immunodiagnosis and immunotherapy

Barry S. Wilson, Patrizio Giacomini, Kohzoh Imai, Pier Giorgio Natali, Toshihiro Nakanishi, Giovanna Ruberto, Soldano Ferrone

Research output: Contribution to journalArticle

Abstract

Using monoclonal antibodies three types of membrane-bound tumour-associated antigens have been identified on human melanoma cells. The tissue distribution, the immunological profile and the structural properties of these melanoma-associated antigens (MAA) are described. The applications of the monoclonal antibodies to one of the MAA in the area of immunodiagnosis and immunotherapy are discussed.

Original languageEnglish
Pages (from-to)517-538
Number of pages22
JournalLa Ricerca in Clinica e in Laboratorio
Volume12
Issue number4
DOIs
Publication statusPublished - Oct 1982

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Keywords

  • Immunochemistry
  • Immunodiagnosis
  • Immunofluorescence
  • Immunotherapy
  • Monoclonal antibodies
  • Tumour-associated antigens

ASJC Scopus subject areas

  • Clinical Biochemistry

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