Human papilloma virus (HPV) in head and neck region: Review of literature

L. Mannarini, V. Kratochvil, L. Calabrese, L. Gomes Silva, P. Morbini, J. Betka, M. Benazzo

Research output: Contribution to journalArticle

Abstract

The evidence that human papillomavirus infection is related to head and neck squamous cell carcinoma is supported by molecular and epidemiological data. The definition of a distinct subset of head and neck squamous cell carcinoma, independent of the traditional risk factors and with different clinical presentation and outcome, has led to increasing interest in human papillomavirus infection. This review summarizes current knowledge regarding human papillomavirus biology, oncogenic mechanisms, risk factors for transmission, clinical significance and prophylactic strategies.

Original languageEnglish
Pages (from-to)119-126
Number of pages8
JournalActa Otorhinolaryngologica Italica
Volume29
Issue number3
Publication statusPublished - Jun 2009

Keywords

  • Head and neck
  • Human papillomavirus
  • Oral cavity
  • Oropharynx
  • Squamous cell carcinoma

ASJC Scopus subject areas

  • Otorhinolaryngology

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    Mannarini, L., Kratochvil, V., Calabrese, L., Silva, L. G., Morbini, P., Betka, J., & Benazzo, M. (2009). Human papilloma virus (HPV) in head and neck region: Review of literature. Acta Otorhinolaryngologica Italica, 29(3), 119-126.