Human papillomavirus (HPV)-associated trilateral squamous neoplasia in immunocompetent individual

Alfonso Iovieno; Simonetta Piana; Laura Chiesi; Cristina Fodero; Luigi Fontana

doi:10.1007/s10792-017-0573-8

Human papillomavirus (HPV)-associated trilateral squamous neoplasia in immunocompetent individual

Alfonso Iovieno, Simonetta Piana, Laura Chiesi, Cristina Fodero, Luigi Fontana

Arcispedale Santa Maria Nuova

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: To describe a case of bilateral conjunctival and cervical human papillomavirus (HPV)-related squamous neoplasia. Case description: A healthy immunocompetent 55-year-old lady came to our attention for prosecution of care of a right recurrent conjunctival squamous cell carcinoma. Upon examination, she was found disease-free in the right eye but displayed a left conjunctival intraepithelial neoplasia (CIN grade I) and low-grade cervical squamous dysplasia. HPV infection with genotypes 16 (right eye), 11 and 39 (left eye) and 39 (uterine cervix) was also detected. Conclusion: Simultaneous uterine and conjunctival HPV-related squamous neoplasia can occur in immunocompetent individuals. Auto-inoculation and repeated exposure to HPV could explain coexistence of different genotypes.

Original language	English
Pages (from-to)	1-4
Number of pages	4
Journal	International Ophthalmology
DOIs	https://doi.org/10.1007/s10792-017-0573-8
Publication status	Accepted/In press - Jun 6 2017

Keywords

Conjunctiva
HPV
Neoplasia
OSSN

ASJC Scopus subject areas

Ophthalmology

Access to Document

10.1007/s10792-017-0573-8

Cite this

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abstract = "Purpose: To describe a case of bilateral conjunctival and cervical human papillomavirus (HPV)-related squamous neoplasia. Case description: A healthy immunocompetent 55-year-old lady came to our attention for prosecution of care of a right recurrent conjunctival squamous cell carcinoma. Upon examination, she was found disease-free in the right eye but displayed a left conjunctival intraepithelial neoplasia (CIN grade I) and low-grade cervical squamous dysplasia. HPV infection with genotypes 16 (right eye), 11 and 39 (left eye) and 39 (uterine cervix) was also detected. Conclusion: Simultaneous uterine and conjunctival HPV-related squamous neoplasia can occur in immunocompetent individuals. Auto-inoculation and repeated exposure to HPV could explain coexistence of different genotypes.",

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doi = "10.1007/s10792-017-0573-8",

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T1 - Human papillomavirus (HPV)-associated trilateral squamous neoplasia in immunocompetent individual

AU - Iovieno, Alfonso

AU - Piana, Simonetta

AU - Chiesi, Laura

AU - Fodero, Cristina

AU - Fontana, Luigi

PY - 2017/6/6

Y1 - 2017/6/6

N2 - Purpose: To describe a case of bilateral conjunctival and cervical human papillomavirus (HPV)-related squamous neoplasia. Case description: A healthy immunocompetent 55-year-old lady came to our attention for prosecution of care of a right recurrent conjunctival squamous cell carcinoma. Upon examination, she was found disease-free in the right eye but displayed a left conjunctival intraepithelial neoplasia (CIN grade I) and low-grade cervical squamous dysplasia. HPV infection with genotypes 16 (right eye), 11 and 39 (left eye) and 39 (uterine cervix) was also detected. Conclusion: Simultaneous uterine and conjunctival HPV-related squamous neoplasia can occur in immunocompetent individuals. Auto-inoculation and repeated exposure to HPV could explain coexistence of different genotypes.

AB - Purpose: To describe a case of bilateral conjunctival and cervical human papillomavirus (HPV)-related squamous neoplasia. Case description: A healthy immunocompetent 55-year-old lady came to our attention for prosecution of care of a right recurrent conjunctival squamous cell carcinoma. Upon examination, she was found disease-free in the right eye but displayed a left conjunctival intraepithelial neoplasia (CIN grade I) and low-grade cervical squamous dysplasia. HPV infection with genotypes 16 (right eye), 11 and 39 (left eye) and 39 (uterine cervix) was also detected. Conclusion: Simultaneous uterine and conjunctival HPV-related squamous neoplasia can occur in immunocompetent individuals. Auto-inoculation and repeated exposure to HPV could explain coexistence of different genotypes.

KW - Conjunctiva

KW - HPV

KW - Neoplasia

KW - OSSN

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Human papillomavirus (HPV)-associated trilateral squamous neoplasia in immunocompetent individual

Abstract

Keywords

ASJC Scopus subject areas

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