Human placental Hofbauer cells promote mitogen induced T cell proliferation.

D. Zaccheo; V. Pistoia; C. Martinoli

Human placental Hofbauer cells promote mitogen induced T cell proliferation.

D. Zaccheo, V. Pistoia, C. Martinoli

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

Hofbauer cells are a major cell type of the human placental villous core particularly numerous at the beginning of pregnancy. In the present study we have investigated whether or not Hofbauer cells could subserve the function of accessory cells for colony formation by phytohemagglutinin stimulated allogeneic T cells. Results showed that Hofbauer cells are capable to play an accessory role on T cell proliferation probably due to the release of interleukin 1-like soluble factors.

Original language	English
Pages (from-to)	1879-1884
Number of pages	6
Journal	Bollettino della Societa Italiana di Biologia Sperimentale
Volume	60
Issue number	10
Publication status	Published - Oct 30 1984

ASJC Scopus subject areas

Medicine(all)

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title = "Human placental Hofbauer cells promote mitogen induced T cell proliferation.",

abstract = "Hofbauer cells are a major cell type of the human placental villous core particularly numerous at the beginning of pregnancy. In the present study we have investigated whether or not Hofbauer cells could subserve the function of accessory cells for colony formation by phytohemagglutinin stimulated allogeneic T cells. Results showed that Hofbauer cells are capable to play an accessory role on T cell proliferation probably due to the release of interleukin 1-like soluble factors.",

author = "D. Zaccheo and V. Pistoia and C. Martinoli",

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AU - Pistoia, V.

AU - Martinoli, C.

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N2 - Hofbauer cells are a major cell type of the human placental villous core particularly numerous at the beginning of pregnancy. In the present study we have investigated whether or not Hofbauer cells could subserve the function of accessory cells for colony formation by phytohemagglutinin stimulated allogeneic T cells. Results showed that Hofbauer cells are capable to play an accessory role on T cell proliferation probably due to the release of interleukin 1-like soluble factors.

AB - Hofbauer cells are a major cell type of the human placental villous core particularly numerous at the beginning of pregnancy. In the present study we have investigated whether or not Hofbauer cells could subserve the function of accessory cells for colony formation by phytohemagglutinin stimulated allogeneic T cells. Results showed that Hofbauer cells are capable to play an accessory role on T cell proliferation probably due to the release of interleukin 1-like soluble factors.

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