Some case reports and case series suggest that protein C concentrates may improve the outcome in patients with congenital or acquired protein C deficiency (not only in those with sepsis induced purpura fulminans). We reviewed the published literature on the use of protein C concentrates in adult septic patients and found that it is limited to less than 70 patients reported in observational studies with a 70% survival, and added our personal experience (two adult patients with sepsis and contraindications to recombinant activated protein C).
|Number of pages||5|
|Publication status||Published - 2008|
- Cardiac surgery
- Protein C
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine
- Emergency Medicine