Human–animal interface: The case for influenza interspecies transmission

Isabella Donatelli, Maria R. Castrucci, Maria A. De Marco, Mauro Delogu, Robert G. Webster

Research output: Chapter in Book/Report/Conference proceedingChapter


Since the 1990s, the threat of influenza viruses to veterinary and human public health has increased. This coincides with the larger global populations of poultry, pigs, and people and with changing ecological factors. These factors include the redistribution of the human population to cities, rapid mass transportation of people and infectious agents, increased global land use, climate change, and possible changes in viral ecology that perpetuate highly pathogenic influenza viruses in the aquatic bird reservoir. The emergence of H5N1, H7N9, and H9N2 subtypes of influenza A virus and the increased genetic exchange among influenza viruses in wild aquatic birds, domestic poultry, swine, and humans pose a continuing threat to humanity. Here we consider the fundamental and practical knowledge of influenza A viruses at the human–animal interfaces to facilitate the development of novel control strategies and modified agricultural practices that will reduce or prevent interspecies transmission.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Number of pages17
Publication statusPublished - Jan 1 2017

Publication series

NameAdvances in Experimental Medicine and Biology
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019


  • Avian influenza
  • H5N1
  • H7N9
  • Zoonosis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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