Hybrid anatomo-functional imaging of coronary artery disease: Beneficial irrespective of its core components

Francesco Nudi, Giuseppe Biondi-Zoccai, Andrea Romagnoli, Orazio Schillaci, Alessandro Nudi, Francesco Versaci

Research output: Contribution to journalArticle

Abstract

Coronary artery disease (CAD) is the most common and important cause of ischemic heart disease, with major implications on global morbidity and mortality. Non-invasive testing is crucial in the diagnostic and prognostic work-up of patients with or at risk of CAD, and also to guide decision making in terms of pharmacologic and revascularization therapy. The traditional paradigm is to view anatomic (i.e., coronary computed tomography) and functional imaging (e.g., myocardial perfusion scintigraphy) tests as opposing alternatives. Such approach is too reductionist and does not capitalize on the strengths of each type of test while risking to overlook the inherent limitations. The combination of anatomic and functional tests in a logic of hybrid imaging holds the promise of overcoming the limitations inherent to anatomic and functional testing, enabling more accurate diagnosis, prognosis, and guidance for revascularization in patients with CAD.

Original languageEnglish
JournalJournal of Nuclear Cardiology
DOIs
Publication statusAccepted/In press - Jan 1 2018

Keywords

  • computed tomography
  • Coronary artery disease
  • hybrid imaging
  • single-photon emission computed tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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