Hybrid Indocyanine Green–99mTc-nanocolloid for Single-photon Emission Computed Tomography and Combined Radio- and Fluorescence-guided Sentinel Node Biopsy in Penile Cancer: Results of 740 Inguinal Basins Assessed at a Single Institution

Paolo Dell'Oglio, Hielke M. de Vries, Elio Mazzone, Gijs H. KleinJan, Maarten L. Donswijk, Henk G. van der Poel, Simon Horenblas, Fijs W.B. van Leeuwen, Oscar R. Brouwer

Research output: Contribution to journalArticlepeer-review

Abstract

Indocyanine green (ICG)-99mTc-nanocolloid is safe and allows for accurate preoperative sentinel node (SN) identification in penile cancer patients, while enabling both intraoperative radio- and fluorescence-guided SN localisation. Fluorescence guidance provided by hybrid ICG-99mTc-nanocolloid vastly improves intraoperative optical SN identification compared with blue dye.

Original languageEnglish
Pages (from-to)865-872
Number of pages8
JournalEuropean Urology
Volume78
Issue number6
DOIs
Publication statusPublished - Dec 2020

Keywords

  • Blue dye
  • Fluorescence
  • Indocyanine green
  • Penile cancer
  • Sentinel node

ASJC Scopus subject areas

  • Urology

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