Hybrid minimally invasive esophagectomy for cancer: Impact on postoperative inflammatory and nutritional status

M. Scarpa, F. Cavallin, L. M. Saadeh, E. Pinto, R. Alfieri, M. Cagol, A. Da Roit, E. Pizzolato, G. Noaro, G. Pozza, C. Castoro

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The purpose of this case-control study was to evaluate the impact of hybrid minimally invasive esophagectomy for cancer on surgical stress response and nutritional status. All 34 consecutive patients undergoing hybrid minimally invasive esophagectomy for cancer at our surgical unit between 2008 and 2013 were retrospectively compared with 34 patients undergoing esophagectomy with open gastric tubulization (open), matched for neoadjuvant therapy, pathological stage, gender and age. Demographic data, tumor features and postoperative course (including quality of life and systemic inflammatory and nutritional status) were compared. Postoperative course was similar in terms of complication rate. Length of stay in intensive care unit was shorter in patients undergoing hybrid minimally invasive esophagectomy (P = 0.002). In the first postoperative day, patients undergoing hybrid minimally invasive esophagectomy had lower C-reactive protein levels (P = 0.001) and white cell blood count (P = 0.05), and higher albumin serum level (P = 0.001). In this group, albumin remained higher also at third (P = 0.06) and seventh (P = 0.008) postoperative day, and C-reactive protein resulted lower at third post day (P = 0.04). Hybrid minimally invasive esophagectomy significantly improved the systemic inflammatory and catabolic response to surgical trauma, contributing to a shorter length of stay in intensive care unit.

Original languageEnglish
Pages (from-to)1064-1070
Number of pages7
JournalDiseases of the Esophagus
Volume29
Issue number8
DOIs
Publication statusPublished - Dec 1 2016

Fingerprint

Esophagectomy
Nutritional Status
Neoplasms
C-Reactive Protein
Intensive Care Units
Length of Stay
Neoadjuvant Therapy
Leukocyte Count
Serum Albumin
Case-Control Studies
Albumins
Stomach
Quality of Life
Demography
Wounds and Injuries

Keywords

  • Esophageal cancer
  • Esophagectomy
  • Inflammation response
  • Minimally invasive

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Hybrid minimally invasive esophagectomy for cancer : Impact on postoperative inflammatory and nutritional status. / Scarpa, M.; Cavallin, F.; Saadeh, L. M.; Pinto, E.; Alfieri, R.; Cagol, M.; Da Roit, A.; Pizzolato, E.; Noaro, G.; Pozza, G.; Castoro, C.

In: Diseases of the Esophagus, Vol. 29, No. 8, 01.12.2016, p. 1064-1070.

Research output: Contribution to journalArticle

@article{fa9692dbdde44ceca503dee5e271ab12,
title = "Hybrid minimally invasive esophagectomy for cancer: Impact on postoperative inflammatory and nutritional status",
abstract = "The purpose of this case-control study was to evaluate the impact of hybrid minimally invasive esophagectomy for cancer on surgical stress response and nutritional status. All 34 consecutive patients undergoing hybrid minimally invasive esophagectomy for cancer at our surgical unit between 2008 and 2013 were retrospectively compared with 34 patients undergoing esophagectomy with open gastric tubulization (open), matched for neoadjuvant therapy, pathological stage, gender and age. Demographic data, tumor features and postoperative course (including quality of life and systemic inflammatory and nutritional status) were compared. Postoperative course was similar in terms of complication rate. Length of stay in intensive care unit was shorter in patients undergoing hybrid minimally invasive esophagectomy (P = 0.002). In the first postoperative day, patients undergoing hybrid minimally invasive esophagectomy had lower C-reactive protein levels (P = 0.001) and white cell blood count (P = 0.05), and higher albumin serum level (P = 0.001). In this group, albumin remained higher also at third (P = 0.06) and seventh (P = 0.008) postoperative day, and C-reactive protein resulted lower at third post day (P = 0.04). Hybrid minimally invasive esophagectomy significantly improved the systemic inflammatory and catabolic response to surgical trauma, contributing to a shorter length of stay in intensive care unit.",
keywords = "Esophageal cancer, Esophagectomy, Inflammation response, Minimally invasive",
author = "M. Scarpa and F. Cavallin and Saadeh, {L. M.} and E. Pinto and R. Alfieri and M. Cagol and {Da Roit}, A. and E. Pizzolato and G. Noaro and G. Pozza and C. Castoro",
year = "2016",
month = "12",
day = "1",
doi = "10.1111/dote.12418",
language = "English",
volume = "29",
pages = "1064--1070",
journal = "Diseases of the Esophagus",
issn = "1120-8694",
publisher = "Wiley-Blackwell",
number = "8",

}

TY - JOUR

T1 - Hybrid minimally invasive esophagectomy for cancer

T2 - Impact on postoperative inflammatory and nutritional status

AU - Scarpa, M.

AU - Cavallin, F.

AU - Saadeh, L. M.

AU - Pinto, E.

AU - Alfieri, R.

AU - Cagol, M.

AU - Da Roit, A.

AU - Pizzolato, E.

AU - Noaro, G.

AU - Pozza, G.

AU - Castoro, C.

PY - 2016/12/1

Y1 - 2016/12/1

N2 - The purpose of this case-control study was to evaluate the impact of hybrid minimally invasive esophagectomy for cancer on surgical stress response and nutritional status. All 34 consecutive patients undergoing hybrid minimally invasive esophagectomy for cancer at our surgical unit between 2008 and 2013 were retrospectively compared with 34 patients undergoing esophagectomy with open gastric tubulization (open), matched for neoadjuvant therapy, pathological stage, gender and age. Demographic data, tumor features and postoperative course (including quality of life and systemic inflammatory and nutritional status) were compared. Postoperative course was similar in terms of complication rate. Length of stay in intensive care unit was shorter in patients undergoing hybrid minimally invasive esophagectomy (P = 0.002). In the first postoperative day, patients undergoing hybrid minimally invasive esophagectomy had lower C-reactive protein levels (P = 0.001) and white cell blood count (P = 0.05), and higher albumin serum level (P = 0.001). In this group, albumin remained higher also at third (P = 0.06) and seventh (P = 0.008) postoperative day, and C-reactive protein resulted lower at third post day (P = 0.04). Hybrid minimally invasive esophagectomy significantly improved the systemic inflammatory and catabolic response to surgical trauma, contributing to a shorter length of stay in intensive care unit.

AB - The purpose of this case-control study was to evaluate the impact of hybrid minimally invasive esophagectomy for cancer on surgical stress response and nutritional status. All 34 consecutive patients undergoing hybrid minimally invasive esophagectomy for cancer at our surgical unit between 2008 and 2013 were retrospectively compared with 34 patients undergoing esophagectomy with open gastric tubulization (open), matched for neoadjuvant therapy, pathological stage, gender and age. Demographic data, tumor features and postoperative course (including quality of life and systemic inflammatory and nutritional status) were compared. Postoperative course was similar in terms of complication rate. Length of stay in intensive care unit was shorter in patients undergoing hybrid minimally invasive esophagectomy (P = 0.002). In the first postoperative day, patients undergoing hybrid minimally invasive esophagectomy had lower C-reactive protein levels (P = 0.001) and white cell blood count (P = 0.05), and higher albumin serum level (P = 0.001). In this group, albumin remained higher also at third (P = 0.06) and seventh (P = 0.008) postoperative day, and C-reactive protein resulted lower at third post day (P = 0.04). Hybrid minimally invasive esophagectomy significantly improved the systemic inflammatory and catabolic response to surgical trauma, contributing to a shorter length of stay in intensive care unit.

KW - Esophageal cancer

KW - Esophagectomy

KW - Inflammation response

KW - Minimally invasive

UR - http://www.scopus.com/inward/record.url?scp=84945333661&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84945333661&partnerID=8YFLogxK

U2 - 10.1111/dote.12418

DO - 10.1111/dote.12418

M3 - Article

AN - SCOPUS:84945333661

VL - 29

SP - 1064

EP - 1070

JO - Diseases of the Esophagus

JF - Diseases of the Esophagus

SN - 1120-8694

IS - 8

ER -