Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine

Franco de Conno, Augusto Caraceni, Cinzia Martini, Elio Spoldi, Monica Salvetti, Vittorio Ventafridda

Research output: Contribution to journalArticlepeer-review


We report the case of a patient who developed myoclonus and hyperalgesia following administration of high-dose subarachnoid morphine. This complication occurred with 40-80 mg/day continuous infusion. The pathophysiology of these side effects is discussed.

Original languageEnglish
Pages (from-to)337-339
Number of pages3
Issue number3
Publication statusPublished - 1991


  • Hyperalgesia
  • Morphine
  • Myoclonus
  • Subarachnoid infusion

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Neuroscience(all)
  • Neurology
  • Pharmacology
  • Clinical Psychology


Dive into the research topics of 'Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine'. Together they form a unique fingerprint.

Cite this