Hyperamylasemia due to macromylasemia in adult gluten enteropathy

G. Bonetti, G. Serricchio, A. Giudici, M. Bettonagli, G. B. Vadacca, R. Bruno, E. Coslovich, R. Moratti

Research output: Contribution to journalArticlepeer-review

Abstract

We report hyperamylasemia due to macroamylasemia in a 33-year-old-woman with gluten enteropathy. Macroamylasemia was demonstrated by precipitation of 97% of amylase activity with PEG 6000. It was associated with increased serum IgA, with elevated values of specific IgA antibodies against α-gliadin and with a high titre of IgA anti-endomysium antibodies. Macroamylasemia disappeared after 2 months of a strict gluten-free diet. These data suggest that the increased IgA concentration in adult gluten enteropathy led to increased macroamylase formation.

Original languageEnglish
Pages (from-to)271-274
Number of pages4
JournalScandinavian Journal of Clinical and Laboratory Investigation
Volume57
Issue number3
Publication statusPublished - 1997

Keywords

  • Anti-endomysium antibodies
  • Anti-gliadin antibodies
  • Coeliac disease
  • Hyperamylasemia
  • Macroamylasemia

ASJC Scopus subject areas

  • Clinical Biochemistry

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