Abstract
The presence of a high incidence of thrombotic events, mainly in nontransfusion-dependent β-thalassemia syndromes, has led to the identification of a hypercoagulable state in thalassemia patients. This article highlights the mechanisms leading to hypercoagulability in thalassemia. It also discusses the clinical experience and available evidence on prevention and management approaches.
| Original language | English |
|---|---|
| Pages (from-to) | 237-245 |
| Number of pages | 9 |
| Journal | Hematology/Oncology Clinics of North America |
| Volume | 32 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 1 2018 |
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Keywords
- Cerebrovascular disease
- Hypercoagulable state
- Pulmonary hypertension
- Thrombosis
ASJC Scopus subject areas
- Hematology
- Oncology
Cite this
Hypercoagulability and Vascular Disease. / Taher, Ali T.; Cappellini, Maria Domenica; Bou-Fakhredin, Rayan; Coriu, Daniel; Musallam, Khaled M.
In: Hematology/Oncology Clinics of North America, Vol. 32, No. 2, 01.04.2018, p. 237-245.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Hypercoagulability and Vascular Disease
AU - Taher, Ali T.
AU - Cappellini, Maria Domenica
AU - Bou-Fakhredin, Rayan
AU - Coriu, Daniel
AU - Musallam, Khaled M.
PY - 2018/4/1
Y1 - 2018/4/1
N2 - The presence of a high incidence of thrombotic events, mainly in nontransfusion-dependent β-thalassemia syndromes, has led to the identification of a hypercoagulable state in thalassemia patients. This article highlights the mechanisms leading to hypercoagulability in thalassemia. It also discusses the clinical experience and available evidence on prevention and management approaches.
AB - The presence of a high incidence of thrombotic events, mainly in nontransfusion-dependent β-thalassemia syndromes, has led to the identification of a hypercoagulable state in thalassemia patients. This article highlights the mechanisms leading to hypercoagulability in thalassemia. It also discusses the clinical experience and available evidence on prevention and management approaches.
KW - Cerebrovascular disease
KW - Hypercoagulable state
KW - Pulmonary hypertension
KW - Thrombosis
UR - http://www.scopus.com/inward/record.url?scp=85035226573&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85035226573&partnerID=8YFLogxK
U2 - 10.1016/j.hoc.2017.11.001
DO - 10.1016/j.hoc.2017.11.001
M3 - Review article
AN - SCOPUS:85035226573
VL - 32
SP - 237
EP - 245
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
SN - 0889-8588
IS - 2
ER -