Hypercoagulability and Vascular Disease

Ali T. Taher, Maria Domenica Cappellini, Rayan Bou-Fakhredin, Daniel Coriu, Khaled M. Musallam

Research output: Contribution to journalReview articlepeer-review


The presence of a high incidence of thrombotic events, mainly in nontransfusion-dependent β-thalassemia syndromes, has led to the identification of a hypercoagulable state in thalassemia patients. This article highlights the mechanisms leading to hypercoagulability in thalassemia. It also discusses the clinical experience and available evidence on prevention and management approaches.

Original languageEnglish
Pages (from-to)237-245
Number of pages9
JournalHematology/Oncology Clinics of North America
Issue number2
Publication statusPublished - Apr 1 2018


  • Cerebrovascular disease
  • Hypercoagulable state
  • Pulmonary hypertension
  • Thrombosis

ASJC Scopus subject areas

  • Hematology
  • Oncology


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