Hyperglycaemia and β-cell antibodies: Is it always pre-type 1 diabetes?

Giuseppe D'Annunzio, Marta Marchi, Concetta Aloi, Alessandro Salina, Francesca Lugani, Renata Lorini

Research output: Contribution to journalArticlepeer-review

Abstract

We describe 10-year-old girl with mild incidental hyperglycaemia, impaired glucose tolerance and GADA positivity. Family history for mild hyperglycaemia and GADA fluctuation alerted us to a possible MODY diagnosis which was confirmed by detection of GCK mutation c.626C>T; p.T209M. Weak or transient β-cell autoimmunity should not preclude genetic testing for MODY when the clinical features are suggestive.

Original languageEnglish
JournalDiabetes Research and Clinical Practice
Volume100
Issue number1
DOIs
Publication statusPublished - Apr 2013

Keywords

  • β-Cell antibodies
  • Hyperglycaemia
  • MODY
  • Pre-type 1 diabetes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Endocrinology

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