Iperomocisteinemia: Un fattore di rischio per malattia trombotica arteriosa e venosa

Translated title of the contribution: Hyperhomocysteinemia: A risk factor for arterial and venous thrombosis

M. Cattaneo, M. L. Zighetti, R. Lombardi, A. Lecchi

Research output: Contribution to journalArticlepeer-review


In the lost two decades, retrospective case-control studies and prospective cohort studies have demonstrated that moderate hyperhomocysteinemia is a frequent and independent risk factor for premature vascular disease in the coronary, cerebral and peripheral arteries. More recently, the association of moderate hyperhomocysteinemia with venous thrombosis has been shown. Genetic and environmental factors act in concert to cause moderate hyperhomocysteinemia. Since inadequate intake of folic acid, vitamin B12 or vitamin B6 are most frequently associated with hyperhomocysteinemia, particularly in the elderly, it is likely that dietary supplementation of these vitamins could have a tremendous impact on the epidemiology and natural history of thrombotic diseases.

Translated title of the contributionHyperhomocysteinemia: A risk factor for arterial and venous thrombosis
Original languageItalian
Pages (from-to)160-165
Number of pages6
JournalAnnali Italiani di Medicina Interna
Issue number3
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Internal Medicine


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