LA SINDROME DA IPERIMMUNOGLOBULINEMIA E ASSOCIATA AD INFEZIONI RICORRENTI

Translated title of the contribution: Hyperimmunoglobulinemia E syndrome with recurrent infections

P. Rossi, R. D'Amelio, E. Galli, L. Businco

Research output: Contribution to journalArticle

Abstract

Patients suffering from this syndrome have several immunologic dysfunctions: abnormal neutrophil chemotactic responsiveness, T lymphocyte dysfunction and depressed or absent staphylococcal hemolitic titre. Another common characteristic feature is a striking increase of blood eosinophils. Recent experimental investigations have suggested that abnormal leukocyte chemotaxis defect is due to a high level of serum histamine. The inhibitory effect of this inflammation's mediator could be related to an H2 receptor interaction. Clinical aspects of the disorder and the possible therapy are discussed, with regard to Levamisole treatment.

Translated title of the contributionHyperimmunoglobulinemia E syndrome with recurrent infections
Original languageItalian
Pages (from-to)40-45
Number of pages6
JournalFolia Allergologica et Immunologica Clinica
Volume26
Issue number1
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Immunology and Allergy

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