TY - JOUR
T1 - Hyperinsulinemia and insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. The GISIR database
AU - Bonora, Enzo
AU - Capaldo, Brunella
AU - Perin, Paolo Cavallo
AU - del Prato, Stefano
AU - de Mattia, Giancarlo
AU - Frittitta, Lucia
AU - Frontoni, Simona
AU - Leonetti, Frida
AU - Luzi, Livio
AU - Marchesini, Giulio
AU - Marini, Maria Adelaide
AU - Natali, Andrea
AU - Paolisso, Giuseppe
AU - Piatti, Pier Marco
AU - Pujia, Arturo
AU - Solini, Anna
AU - Vettor, Roberto
AU - Bonadonna, Riccardo C.
AU - Ferrannini, Ele
AU - Baratta, Roberto
AU - Graci, Salvatore
AU - Bracaglia, Daniela
AU - Monti, Lucilla
AU - Setola, Emanuela
AU - Montalcini, Tiziana
AU - Sesti, Giorgio
AU - de Kreutzenberg, Saula Vigili
PY - 2008/11
Y1 - 2008/11
N2 - Background and aims: We evaluated whether hyperinsulinemia and/or insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. Methods and results: A database of non-diabetic Italian subjects has recently been set up using data from hyperinsulinemic euglycemic clamp studies carried out using the standard technique (40 mU per min per square meter of body surface area). In this database we evaluated the relationships between fasting plasma insulin (FPI), glucose metabolized during clamp (M) and plasma levels of triglycerides (TG), high density lipoprotein cholesterol (HDL-C), uric acid (UA) as well as blood pressure (BP) in non-diabetic subjects with fasting plasma glucose
AB - Background and aims: We evaluated whether hyperinsulinemia and/or insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. Methods and results: A database of non-diabetic Italian subjects has recently been set up using data from hyperinsulinemic euglycemic clamp studies carried out using the standard technique (40 mU per min per square meter of body surface area). In this database we evaluated the relationships between fasting plasma insulin (FPI), glucose metabolized during clamp (M) and plasma levels of triglycerides (TG), high density lipoprotein cholesterol (HDL-C), uric acid (UA) as well as blood pressure (BP) in non-diabetic subjects with fasting plasma glucose
KW - Blood pressure
KW - HDL-cholesterol
KW - Insulin
KW - Insulin resistance
KW - Triglycerides
KW - Uric acid
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UR - http://www.scopus.com/inward/citedby.url?scp=54049089061&partnerID=8YFLogxK
U2 - 10.1016/j.numecd.2007.05.002
DO - 10.1016/j.numecd.2007.05.002
M3 - Article
C2 - 18060751
AN - SCOPUS:54049089061
VL - 18
SP - 624
EP - 631
JO - Nutrition, Metabolism and Cardiovascular Diseases
JF - Nutrition, Metabolism and Cardiovascular Diseases
SN - 0939-4753
IS - 9
ER -