Hyperprolactinemia as the first symptom of craniopharyngioma

G. Maira, C. Di Rocco, C. Anile, R. Roselli

Research output: Contribution to journalArticlepeer-review

Abstract

The endocrinological alterations related to craniopharyngiomas are usually described as panhypopituitarism. The growth failure in the prcpuberal child and/or the puberal retard are the clinical symptoms usually related to it. Nevertheless, for the peculiar diencephalic control of the prolactin (PRL) pituitary secretion, different endocrinological pictures can be observed, related to the different degree of pituitary-hypothalamic compression from the craniopharyngioma. For these reasons a dynamic PRL pre- and postoperative evaluation has been performed in 4 patients operated on for craniopharyngioma. A correlation has been made between hormonal picture, size and location of the tumor, and surgical results. The value of these data in performing an early diagnosis in children with craniopharyngioma is discussed.

Original languageEnglish
Pages (from-to)205-210
Number of pages6
JournalPediatric Neurosurgery
Volume9
Issue number3-4
DOIs
Publication statusPublished - 1982

Keywords

  • Craniopharyngiomas
  • Hypothalamus
  • Pituitary stalk
  • Prolactin

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Surgery

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