Hypertension and the heart

Giuseppe Mancia, Francesco Scopelliti, Guido Grassi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The interactions linking high blood pressure with hypertensive heart disease are reciprocal. Hypertension can be regarded as a source of adverse effects on myocardial structure and function by favoring the development and progression of left ventricular hypertrophy and of left ventricular dysfunction and failure in the advanced phases of the disease. Conversely, the heart can be regarded as a source of reflex influences on the cardiovascular system, which appear to be deranged in the hypertensive state. The clinical relevance of this reflex dysfunction is based on the evidence that these alterations may favor the occurrence of an increased sympathetic vasoconstrictor drive, thereby promoting the development of the1 hypertensive state. Both phenomena have important clinic and therapeutic implications potentiating the cardiovascular risk profile of the hypertensive patient.

Original languageEnglish
Pages (from-to)198-202
Number of pages5
JournalSeminars in Cardiothoracic and Vascular Anesthesia
Volume10
Issue number3
DOIs
Publication statusPublished - Sep 2006

Fingerprint

Reflex
Hypertension
Left Ventricular Dysfunction
Left Ventricular Hypertrophy
Vasoconstrictor Agents
Cardiovascular System
Heart Diseases
Therapeutics
Drive

Keywords

  • Cardiopulmonary reflex
  • Hypertension
  • Left ventricular hypertrophy

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Hypertension and the heart. / Mancia, Giuseppe; Scopelliti, Francesco; Grassi, Guido.

In: Seminars in Cardiothoracic and Vascular Anesthesia, Vol. 10, No. 3, 09.2006, p. 198-202.

Research output: Contribution to journalArticle

Mancia, Giuseppe ; Scopelliti, Francesco ; Grassi, Guido. / Hypertension and the heart. In: Seminars in Cardiothoracic and Vascular Anesthesia. 2006 ; Vol. 10, No. 3. pp. 198-202.
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