Abstract
The interactions linking high blood pressure with hypertensive heart disease are reciprocal. Hypertension can be regarded as a source of adverse effects on myocardial structure and function by favoring the development and progression of left ventricular hypertrophy and of left ventricular dysfunction and failure in the advanced phases of the disease. Conversely, the heart can be regarded as a source of reflex influences on the cardiovascular system, which appear to be deranged in the hypertensive state. The clinical relevance of this reflex dysfunction is based on the evidence that these alterations may favor the occurrence of an increased sympathetic vasoconstrictor drive, thereby promoting the development of the1 hypertensive state. Both phenomena have important clinic and therapeutic implications potentiating the cardiovascular risk profile of the hypertensive patient.
| Original language | English |
|---|---|
| Pages (from-to) | 198-202 |
| Number of pages | 5 |
| Journal | Seminars in Cardiothoracic and Vascular Anesthesia |
| Volume | 10 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 2006 |
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Keywords
- Cardiopulmonary reflex
- Hypertension
- Left ventricular hypertrophy
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
Hypertension and the heart. / Mancia, Giuseppe; Scopelliti, Francesco; Grassi, Guido.
In: Seminars in Cardiothoracic and Vascular Anesthesia, Vol. 10, No. 3, 09.2006, p. 198-202.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hypertension and the heart
AU - Mancia, Giuseppe
AU - Scopelliti, Francesco
AU - Grassi, Guido
PY - 2006/9
Y1 - 2006/9
N2 - The interactions linking high blood pressure with hypertensive heart disease are reciprocal. Hypertension can be regarded as a source of adverse effects on myocardial structure and function by favoring the development and progression of left ventricular hypertrophy and of left ventricular dysfunction and failure in the advanced phases of the disease. Conversely, the heart can be regarded as a source of reflex influences on the cardiovascular system, which appear to be deranged in the hypertensive state. The clinical relevance of this reflex dysfunction is based on the evidence that these alterations may favor the occurrence of an increased sympathetic vasoconstrictor drive, thereby promoting the development of the1 hypertensive state. Both phenomena have important clinic and therapeutic implications potentiating the cardiovascular risk profile of the hypertensive patient.
AB - The interactions linking high blood pressure with hypertensive heart disease are reciprocal. Hypertension can be regarded as a source of adverse effects on myocardial structure and function by favoring the development and progression of left ventricular hypertrophy and of left ventricular dysfunction and failure in the advanced phases of the disease. Conversely, the heart can be regarded as a source of reflex influences on the cardiovascular system, which appear to be deranged in the hypertensive state. The clinical relevance of this reflex dysfunction is based on the evidence that these alterations may favor the occurrence of an increased sympathetic vasoconstrictor drive, thereby promoting the development of the1 hypertensive state. Both phenomena have important clinic and therapeutic implications potentiating the cardiovascular risk profile of the hypertensive patient.
KW - Cardiopulmonary reflex
KW - Hypertension
KW - Left ventricular hypertrophy
UR - http://www.scopus.com/inward/record.url?scp=33747117972&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33747117972&partnerID=8YFLogxK
U2 - 10.1177/1089253206291315
DO - 10.1177/1089253206291315
M3 - Article
C2 - 16959750
AN - SCOPUS:33747117972
VL - 10
SP - 198
EP - 202
JO - Seminars in Cardiothoracic and Vascular Anesthesia
JF - Seminars in Cardiothoracic and Vascular Anesthesia
SN - 1089-2532
IS - 3
ER -