Hypertension in diabetes: an additional factor determining autonomic neuropathy?

L. Ricordi, M. Rossi, G. Marti, G. Finardi, P. Fratino, L. Bernardi

Research output: Contribution to journalArticlepeer-review


Cardiac autonomic function was investigated in 64 normotensive diabetics [24 IDDM, 40 NIDDM, 42 males and 22 females, age (mean ± SD) 51.64 ± 12.06 years (range 26-72)] and in 23 hypertensive diabetics [4 IDDM, 19 NIDDM, 12 males and 11 females, mean age 53.30 ± 10.27 years (31-67)], by means of the 4 standard autonomic tests based on cardiovascular reflexes: deep breathing, the Valsalva manoeuvre, standing and handgrip. In addition, we performed the cross-correlation test, a computerized method based on spectral analysis of the heart rate and respiration fluctuations. Hypertensive diabetics showed a higher prevalence of abnormal autonomic tests than normotensive diabetics: cross-correlation function was altered in 10/23 hypertensive vs 14/64 normotensive diabetics (p

Original languageEnglish
Pages (from-to)269-275
Number of pages7
JournalDiabetes, Nutrition and Metabolism - Clinical and Experimental
Issue number4
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Internal Medicine
  • Endocrinology
  • Food Science
  • Endocrinology, Diabetes and Metabolism


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