Hypertension in young patients after renal transplantation: Ambulatory blood pressure monitoring versus casual blood pressure

Armando Calzolari, Ugo Giordano, Maria Chiara Matteucci, Enrica Pastore, Attilio Turchetta, Gianfranco Rizzoni, Bruce Alpert

Research output: Contribution to journalArticle

Abstract

The results of ambulatory blood pressure monitoring (ABPM) in children after kidney transplant were analyzed to ascertain any alteration in circadian BP profile, degree of hypertension, and efficacy of therapy. The data were also compared with casual BP data and left ventricular mass index (LVMI). We have examined 30 patients (17 male, 13 female), mean age 16.1 ± 3.6 years after kidney transplant. All patients were receiving triple immune- suppressive therapy and 20 of them were also taking antihypertensive therapy. They underwent clinical examination with measurement of BP at rest, echocardiogram mono-2D, and ABPM. The following ABPM parameters were recorded: systolic (S) and diastolic (D) BP at rest; mean 24-h SBP and DBP; mean daytime SBP and DBP; mean nighttime SBP and DBP; nocturnal fall in SBP and DBP; and mean daytime and nighttime heart rate (HR). The patients were divided in two groups. Group A consisted of 20 patients taking antihypertensive treatment; group B consisted of 10 patients not taking antihypertensive treatment. Casual and ABPM data for the two groups were compared using the Student t test for unpaired data. Blood pressure at rest and LVMI were not statistically different between the two patient groups. The ABPM data showed statistical differences between the two groups for mean 24- h SBP and DBP, daytime and nighttime SBP, nighttime DBP, fall in nocturnal DBP, and nighttime HR. Mean 24-h SBP and DBP, mean daytime SBP and DBP, and mean nighttime SBP and DBP were significantly correlated to LVMI (respectively, P = .009, P = .005, P = .008, P = .007, P = .05, and P = .01). Twenty-four-hour ABPM was more useful in the diagnosis and management of hypertension than was casual BP at rest.

Original languageEnglish
Pages (from-to)497-501
Number of pages5
JournalAmerican Journal of Hypertension
Volume11
Issue number4 I
DOIs
Publication statusPublished - Apr 1998

Keywords

  • ABPM
  • Casual blood pressure
  • Children
  • Renal transplant

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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