Hypertrophic Donavanosis in a Young Pregnant Woman

C. A. Liverani; D. Lattuada; S. Mangano; C. Pignatari; D. Puglia; E. Monti; G. Bolis

doi:10.1016/j.jpag.2011.10.002

Hypertrophic Donavanosis in a Young Pregnant Woman

C. A. Liverani, D. Lattuada, S. Mangano, C. Pignatari, D. Puglia, E. Monti, G. Bolis

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Donovanosis is a chronic bacterial illness, progressive and indolent, which normally attacks the skin and mucous membranes in the genital and perigenital regions. Case: An 18-year-old pregnant female presented with large, hypertrophic lesions in the ano-genital region. HIV serology was negative. Pap smear revealed a CIN 1 associated with HPV infection. Biopsy yielded macrophages laden with Gram-negative Donovan bodies. Summary and Conclusion: A diagnosis of vulvar and perianal donovanosis was reached; the patient decided to terminate the pregnancy and was treated with azithromycin, which led to clinical resolution.

Original language	English
Journal	Journal of Pediatric and Adolescent Gynecology
Volume	25
Issue number	4
DOIs	https://doi.org/10.1016/j.jpag.2011.10.002
Publication status	Published - Aug 2012

Keywords

Adolescence
Calymmatobacterium
Donovanosis
Klebsiella granulomatis
Pregnancy

ASJC Scopus subject areas

Obstetrics and Gynaecology
Pediatrics, Perinatology, and Child Health

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title = "Hypertrophic Donavanosis in a Young Pregnant Woman",

abstract = "Background: Donovanosis is a chronic bacterial illness, progressive and indolent, which normally attacks the skin and mucous membranes in the genital and perigenital regions. Case: An 18-year-old pregnant female presented with large, hypertrophic lesions in the ano-genital region. HIV serology was negative. Pap smear revealed a CIN 1 associated with HPV infection. Biopsy yielded macrophages laden with Gram-negative Donovan bodies. Summary and Conclusion: A diagnosis of vulvar and perianal donovanosis was reached; the patient decided to terminate the pregnancy and was treated with azithromycin, which led to clinical resolution.",

keywords = "Adolescence, Calymmatobacterium, Donovanosis, Klebsiella granulomatis, Pregnancy",

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T1 - Hypertrophic Donavanosis in a Young Pregnant Woman

AU - Liverani, C. A.

AU - Lattuada, D.

AU - Mangano, S.

AU - Pignatari, C.

AU - Puglia, D.

AU - Monti, E.

AU - Bolis, G.

PY - 2012/8

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N2 - Background: Donovanosis is a chronic bacterial illness, progressive and indolent, which normally attacks the skin and mucous membranes in the genital and perigenital regions. Case: An 18-year-old pregnant female presented with large, hypertrophic lesions in the ano-genital region. HIV serology was negative. Pap smear revealed a CIN 1 associated with HPV infection. Biopsy yielded macrophages laden with Gram-negative Donovan bodies. Summary and Conclusion: A diagnosis of vulvar and perianal donovanosis was reached; the patient decided to terminate the pregnancy and was treated with azithromycin, which led to clinical resolution.

AB - Background: Donovanosis is a chronic bacterial illness, progressive and indolent, which normally attacks the skin and mucous membranes in the genital and perigenital regions. Case: An 18-year-old pregnant female presented with large, hypertrophic lesions in the ano-genital region. HIV serology was negative. Pap smear revealed a CIN 1 associated with HPV infection. Biopsy yielded macrophages laden with Gram-negative Donovan bodies. Summary and Conclusion: A diagnosis of vulvar and perianal donovanosis was reached; the patient decided to terminate the pregnancy and was treated with azithromycin, which led to clinical resolution.

KW - Adolescence

KW - Calymmatobacterium

KW - Donovanosis

KW - Klebsiella granulomatis

KW - Pregnancy

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Hypertrophic Donavanosis in a Young Pregnant Woman

Abstract

Keywords

ASJC Scopus subject areas

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