Hypofractionated breast cancer radiotherapy. Helical tomotherapy in supine position or classic 3DConformal radiotherapy in prone position: Which is better?

Fabrizio Cammarota, Francesca Maria Giugliano, Luciano Iadanza, Luisa Cutillo, Matteo Muto, Diego Toledo, Vincenzo Ravo, Sara Falivene, Paolo Muto

Research output: Contribution to journalArticlepeer-review

Abstract

We propose a comparative dosimetric study of whole-breast hypofractionated radiation therapy using helical tomotherapy (HT) in supine position and 3-D conformal radiotherapy (3D-CRT) in prone position. Twelve patients undergoing breast-conserving therapy were retrospectively selected from October to December 2012. Specific dose-volume parameters were selected for the study. The target coverage was adequate in all patients for both techniques. Significant differences in lung dose distribution were observed: maximum dose (mean value over the 12 plans) was 23.41 Gy in HT plans and 6.65 Gy in 3D-CRT; V20 (i.e. the lung volume receiving 20 Gy) was 0.31% in HT plans and 0.0% in 3D-CRT plans. The mean dose to the heart was 5.57 Gy and 0.93 Gy, respectively. The differences between the two techniques were significant (p

Original languageEnglish
Pages (from-to)1233-1238
Number of pages6
JournalAnticancer Research
Volume34
Issue number3
Publication statusPublished - Mar 1 2014

Keywords

  • 3D conformal radiation therapy
  • Helical tomotherapy
  • Hypofractionated radiation therapy
  • Prone treatment position
  • Supine treatment position

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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