Abstract
Cerebrospinal fluid (CSP) glucose values were measured in 37 HIV-positive patients with neurologic symptoms and in 35 HIV-negative controls affected by bacterial or viral meningo-encephalitis (ME). Low CSF glucose values were found more frequently in HIV+ patients (49% of cases) than in ME patients (14%). CSF/serum ratios for glucose were also significantly lower in HIV +. Mean serum glucose did not differ between the two groups. Since HIV is a strongly neurotropic and infects early the endothelial cells of the brain capillaris, where glucose is actively carried from plasma to CSP, it is hypothesized that low CSF glucose in HIV-infected patients with neurological symptoms might be an early sign of CNS invasion by the virus.
| Translated title of the contribution | Hypoglycorrhachia as an early sign of central nervous system infection caused by HIV |
|---|---|
| Original language | Italian |
| Pages (from-to) | 44-45 |
| Number of pages | 2 |
| Journal | Medicina - Rivista della Enciclopedia Medica Italiana |
| Volume | 9 |
| Issue number | 1 |
| Publication status | Published - Jan 1989 |
ASJC Scopus subject areas
- Medicine(all)
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Cite this
Farinelli, M., Camera, M., Del Bono, V., Fiorelli, M. A., Panavese, C., & Valguarnera, F. (1989). La ipoglicorrachia quale possibile indice precoce di infezione del sistema nervoso centrale da parte dell'HIV. Medicina - Rivista della Enciclopedia Medica Italiana, 9(1), 44-45.