La ipoglicorrachia quale possibile indice precoce di infezione del sistema nervoso centrale da parte dell'HIV.

Translated title of the contribution: Hypoglycorrhachia as an early sign of central nervous system infection caused by HIV

M. Farinelli, M. Camera, V. Del Bono, M. A. Fiorelli, C. Panavese, F. Valguarnera

Research output: Contribution to journalArticle

Abstract

Cerebrospinal fluid (CSP) glucose values were measured in 37 HIV-positive patients with neurologic symptoms and in 35 HIV-negative controls affected by bacterial or viral meningo-encephalitis (ME). Low CSF glucose values were found more frequently in HIV+ patients (49% of cases) than in ME patients (14%). CSF/serum ratios for glucose were also significantly lower in HIV +. Mean serum glucose did not differ between the two groups. Since HIV is a strongly neurotropic and infects early the endothelial cells of the brain capillaris, where glucose is actively carried from plasma to CSP, it is hypothesized that low CSF glucose in HIV-infected patients with neurological symptoms might be an early sign of CNS invasion by the virus.

Translated title of the contributionHypoglycorrhachia as an early sign of central nervous system infection caused by HIV
Original languageItalian
Pages (from-to)44-45
Number of pages2
JournalMedicina - Rivista della Enciclopedia Medica Italiana
Volume9
Issue number1
Publication statusPublished - Jan 1989

ASJC Scopus subject areas

  • Medicine(all)

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    Farinelli, M., Camera, M., Del Bono, V., Fiorelli, M. A., Panavese, C., & Valguarnera, F. (1989). La ipoglicorrachia quale possibile indice precoce di infezione del sistema nervoso centrale da parte dell'HIV. Medicina - Rivista della Enciclopedia Medica Italiana, 9(1), 44-45.