Hyponatremia in cirrhosis: Results of a patient population survey

Paolo Angeli, Florence Wong, Hugh Watson, Pere Ginès, C. H F Castelpoggi, M. L. Ferraz, V. G. Bain, G. B. Pomier-Layrargues, F. Wong, S. Milutinovic, Z. Rumboldt, R. Bruha, P. Hulek, J. Lata, D. Guyader, A. Mallat, W. Fleig, A. Gerbes, L. Ujszàszy, P. AngeliG. Pinzello, F. Salerno, K. L. Goh, S. G. Lim, K. M. Fock, L. Ruiz Del Arbol, F. Diaz, P. Ginès, M. Guevara, E. Renner, S. S. Yang, A. T. Blei, G. Garcia-Tsao

Research output: Contribution to journalArticlepeer-review

Abstract

Low serum sodium concentration is an independent predictor of mortality in patients with cirrhosis, but its prevalence and clinical significance is unclear. To evaluate prospectively the prevalence of low serum sodium concentration and the association between serum sodium levels and severity of ascites and complications of cirrhosis, prospective data were collected on 997 consecutive patients from 28 centers in Europe, North and South America, and Asia for a period of 28 days. The prevalence of low serum sodium concentration as defined by a serum sodium concentration ≤135 mmol/L, ≤130 mmol/L, ≤125 mmol/L, and ≤120 mmol/L was 49.4%, 21.6%, 5.7%, and 1.2%, respectively. The prevalence of low serum sodium levels (

Original languageEnglish
Pages (from-to)1535-1542
Number of pages8
JournalHepatology
Volume44
Issue number6
DOIs
Publication statusPublished - Dec 2006

ASJC Scopus subject areas

  • Hepatology

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