Hyposplenism: A comprehensive review. Part II: Clinical manifestations, diagnosis, and management

Basem M. William, Nitika Thawani, Sutthichai Sae-Tia, Gino R. Corazza

Research output: Contribution to journalArticle


In the first part of this review, we described the physiological basis of splenic function and hypofunction. We also described the wide spectrum of diseases that can result in functional hyposplenism. In the second part of this review, we will be discussing the clinical picture, including complications, diagnostic methods, and management of hyposplenism.

Original languageEnglish
Pages (from-to)89-98
Number of pages10
Issue number2
Publication statusPublished - Apr 2007


  • Asplenia
  • Celiac disease
  • Hyposplenism
  • Sickle cell
  • Splenic hypofunction

ASJC Scopus subject areas

  • Hematology

Cite this