Hypothalamus and headaches

Research output: Contribution to journalArticlepeer-review

Abstract

The hypothalamus forms part of the central autonomic network, regulating body homeostasis and controlling pain. To this effect, it is strongly wired to more rostral and caudal areas, in particular the brainstem periaqueductal grey, the locus coeruleus and the median raphe nuclei, all involved in autonomic and sleep mechanisms and also in the descending control of pain perception. The hypothalamus, especially its posterior regions, becomes activated during attacks of the trigeminal autonomic cephalalgias (TACs), while brainstem, especially dorsal pontine, activity shows up during migraine attacks. The hypothalamus and interconnected brainstem areas likely represent the neural sites responsible for the chronobiological features of some headaches, in particular the sleep-related attacks typical of the TACs, migraines and the hypnic headaches.

Original languageEnglish
JournalNeurological Sciences
Volume28
Issue numberSUPPL. 2
DOIs
Publication statusPublished - May 2007

Keywords

  • Autonomic nervous system
  • Cluster headache
  • Headache
  • Hypothalamus
  • Migraine

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Hypothalamus and headaches'. Together they form a unique fingerprint.

Cite this