Hypothermia for brain protection in the non-cardiac arrest patient

N. Stocchetti, R. Zanier, S. Magnoni, K. Canavesi, L. Ghisoni, L. Longhi

Research output: Contribution to journalArticlepeer-review


This review focuses on the potential application of hypothermia in adults suffering traumatic brain injury (TBI). Hypothermia is neuroprotective, reducing the damaging effects of trauma to the brain in a variety of experimental situations, such as brain ischemia and brain injury, but it has failed to demonstrate outcome improvement in a major controlled, randomized trial. The evidence for the use of hypothermia as a protective procedure is scarce and contradictory. However, evidence does suggest that hypothermia is effective in reducing intracranial hypertension after head injury. Since hypothermia has important side effects, further work is necessary before introducing this procedure into clinical practice for TBI.

Original languageEnglish
Pages (from-to)315-318
Number of pages4
JournalMinerva Anestesiologica
Issue number6
Publication statusPublished - Jun 2008


  • Brain injuries
  • Hypothermia
  • Intracranial pressure

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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