Hysteroscopic endometrial resection vs. hysterectomy for abnormal uterine bleeding: Impact on quality of life and sexuality. Evidence from a systematic review of randomized controlled trials

Salvatore G. Vitale, Simone Ferrero, Michal Ciebiera, Fabio Barra, Péter Török, Jan Tesarik, George A. Vilos, Antonio Cianci

Research output: Contribution to journalReview article


Purpose of reviewThe aim of this systematic review is to summarize the current evidence regarding the effectiveness of hysterectomy and hysteroscopic endometrial resection in improving quality of life (QoL), sexual function and psychological wellbeing of women abnormal uterine bleeding.Recent findingsWe performed a systematic literature search in PubMed/MEDLINE and Embase for original studies written in English (registered in PROSPERO 2019 CRD42019133632), using the terms 'endometrial ablation', 'endometrial destruction', 'endometrial resection', 'hysterectomy', 'menorrhagia', 'dysfunctional uterine bleeding', 'quality of life', 'sexuality' published up to April 2019. Our literature search produced 159 records. After exclusions, nine studies were included showing the following results: both types of treatment significantly improve QoL and psychological wellbeing; hysterectomy is associated with higher rates of satisfaction; hysterectomy is not associated with a significant deterioration in sexual function.SummaryHysterectomy is currently more advantageous in terms of improving abnormal uterine bleeding and satisfaction rates than hysteroscopic endometrial destruction techniques. Furthermore, there is some evidence of a greater improvement in general health for women undergoing hysterectomy. However, high-quality prospective randomized controlled trials should be implemented to investigate the effectiveness of hysterectomy and endometrial ablation in the improvement of QoL outcomes in larger patient cohorts.

Original languageEnglish
Pages (from-to)159-165
Number of pages7
JournalCurrent Opinion in Obstetrics and Gynecology
Issue number2
Publication statusPublished - Apr 1 2020



  • abnormal uterine bleeding
  • endometrial resection
  • hysterectomy
  • hysteroscopy
  • quality of life

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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