IANUA: A regional project for the determination of costs in HIV-infected patients

Barbara Giannini, Roberta Gazzarata, Patrizia Orcamo, Caterina Merlano, Giovanni Cenderello, Alberto Venturini, Antonio Di Biagio, Giovanni Mazzarello, Marcello Montefiori, Marta Ameri, Maurizio Setti, Claudio Viscoli, Giovanni Cassola, Mauro Giacomini

Research output: Chapter in Book/Report/Conference proceedingConference contribution


HIV treatment is based on combined antiretroviral therapy (cART) which has substantially improved survival, thus resulting in an increase in patient life expectancy as well as in the cost of HIV-related medical care. Therefore, several cost effectiveness studies were implemented worldwide, with one specifically in the Liguria region (Italy), to compare the annual economic expense in this area for HIV services, and the related improvement in patients health. The IANUA project is intended to implement both cost-effectiveness and cost-utility analysis, therefore data related to clinical indicators and perceived health status were collected, the latter using a questionnaire based on the EQ-5D-3L. Information about the antiretroviral drugs and the relative quantity that a patient withdraws from the hospital pharmacy every month were extracted from the regional 'F-file'. All data gathered were stored in the Ligurian HIV Network, a web platform developed by the DIBRIS - Medinfo laboratory. More than eight hundred questionnaires were collected, and data will be elaborated by economists and psychologists. The first statistical elaborations showed that, as expected, costs increased as the number of therapeutic lines increased. Moreover, the average annual costs for patients whose last CD4 values were below 200 cells/mmc corresponded to the maximum expense recorded, however, the cost for patients with final CD4 counts above 500 cells/mmc was not, as expected, the lowest found. This can be explained by the fact that stabilized patients, who had CD4 values below 500 cells/mmc, did not need very expensive care, while patients with CD4 counts above 500 cells/mmc improved their health status thanks to cART.

Original languageEnglish
Title of host publicationDigital Healthcare Empowering Europeans - Proceedings of MIE 2015
PublisherIOS Press
Number of pages5
ISBN (Print)9781614995111
Publication statusPublished - 2015
Event26th Medical Informatics in Europe Conference, MIE 2015 - Madrid, Spain
Duration: May 27 2015May 29 2015


Other26th Medical Informatics in Europe Conference, MIE 2015


  • AIDS
  • Antiretroviral treatment
  • Cost effectiveness evaluation
  • Data base reporting service in clinical environment
  • direct reuse of clinical data
  • HIV

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management


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