Ibopamine-induced reduction of serum prolactin level and milk secretion in puerperal women

C. Nappi, G. Colace, P. Affinito, M. Taglialatela, G. F. Di Renzo, U. Montemagno, L. Annunziato

Research output: Contribution to journalArticlepeer-review

Abstract

Ibopamine, a peripheral dopamine agonist, was administered to 80 postpartum women to assess its effect on prolactin (PRL) and milk production. The acute administration of 400 mg significantly decreased serum PRL for more than 240 min. Women given ibopamine 400 mg t. d. s. for 5 to 10 days showed suppression of PRL and milk letdown was prevented in the latter group. No side effects were observed on repeated administration. Ibopamine may be a useful alternative to other dopaminergic compounds for the inhibition of puerperal lactation.

Original languageEnglish
Pages (from-to)133-135
Number of pages3
JournalEuropean Journal of Clinical Pharmacology
Volume39
Issue number2
DOIs
Publication statusPublished - Aug 1990

Keywords

  • ibopamine
  • prolactin secretion
  • puerperal lactation

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)

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