TY - JOUR
T1 - Identification and characterization of a new metallo-β-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes
AU - Perilli, Mariagrazia
AU - Caporale, Bibiana
AU - Celenza, Giuseppe
AU - Pellegrini, Cristina
AU - Docquier, Jean Denis
AU - Mezzatesta, Marilina
AU - Rossolini, Gian Maria
AU - Stefani, A.
AU - Amicosante, Gianfranco
PY - 2007/8
Y1 - 2007/8
N2 - A new natural IND-type metallo-β-lactamase variant, IND-5, was identified in a clinical isolate of Chryseobacterium indologenes. IND-5 shared 92.8% and 92.4% amino acid homology with IND-1 and IND-3, respectively. Purified enzyme (pI = 8.8, M r = 25,000) was able to hydrolyze penicillins, some narrow- and expanded-spectrum cephalosporins, and carbapenems but not monobactams.
AB - A new natural IND-type metallo-β-lactamase variant, IND-5, was identified in a clinical isolate of Chryseobacterium indologenes. IND-5 shared 92.8% and 92.4% amino acid homology with IND-1 and IND-3, respectively. Purified enzyme (pI = 8.8, M r = 25,000) was able to hydrolyze penicillins, some narrow- and expanded-spectrum cephalosporins, and carbapenems but not monobactams.
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U2 - 10.1128/AAC.00083-07
DO - 10.1128/AAC.00083-07
M3 - Article
C2 - 17470648
AN - SCOPUS:34547616857
VL - 51
SP - 2988
EP - 2990
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 8
ER -