A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic (T1D) patient a λUni-Zap cDNA library from human diabetic islets. The significance of the identified autoantigens to the disease pathogenesis remains to be elucidated.
- Human islets cDNA libraries
- Type 1 diabetes
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Internal Medicine