Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes

Alessandra Fierabracci, Francesca Saura

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic (T1D) patient a λUni-Zap cDNA library from human diabetic islets. The significance of the identified autoantigens to the disease pathogenesis remains to be elucidated.

Original languageEnglish
JournalDiabetes Research and Clinical Practice
Volume88
Issue number2
DOIs
Publication statusPublished - May 2010

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Protein Disulfide-Isomerases
Voltage-Gated Potassium Channels
Type 1 Diabetes Mellitus
Gene Library
Autoantibodies
Epitopes
Proteins
To autoantigen

Keywords

  • Autoantibodies
  • Autoantigens
  • Human islets cDNA libraries
  • Type 1 diabetes

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

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