Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes

Alessandra Fierabracci, Francesca Saura

Research output: Contribution to journal › Article

7 Citations (Scopus)

Abstract

A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic (T1D) patient a λUni-Zap cDNA library from human diabetic islets. The significance of the identified autoantigens to the disease pathogenesis remains to be elucidated.

Original languageEnglish
JournalDiabetes Research and Clinical Practice
Volume88
Issue number2
DOIs
Publication statusPublished - May 2010

Fingerprint

Protein Disulfide-Isomerases
Voltage-Gated Potassium Channels
Type 1 Diabetes Mellitus
Gene Library
Autoantibodies
Epitopes
Proteins
To autoantigen

Keywords

  • Autoantibodies
  • Autoantigens
  • Human islets cDNA libraries
  • Type 1 diabetes

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes. / Fierabracci, Alessandra; Saura, Francesca.

In: Diabetes Research and Clinical Practice, Vol. 88, No. 2, 05.2010.

Research output: Contribution to journal › Article

Fierabracci, A & Saura, F 2010, 'Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes', Diabetes Research and Clinical Practice, vol. 88, no. 2. https://doi.org/10.1016/j.diabres.2010.01.018
Fierabracci A, Saura F. Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes. Diabetes Research and Clinical Practice. 2010 May;88(2). https://doi.org/10.1016/j.diabres.2010.01.018
Fierabracci, Alessandra ; Saura, Francesca. / Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes. In: Diabetes Research and Clinical Practice. 2010 ; Vol. 88, No. 2.
@article{156167dcbcbb4595928fb442007d3459,
title = "Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes",
abstract = "A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic (T1D) patient a λUni-Zap cDNA library from human diabetic islets. The significance of the identified autoantigens to the disease pathogenesis remains to be elucidated.",
keywords = "Autoantibodies, Autoantigens, Human islets cDNA libraries, Type 1 diabetes",
author = "Alessandra Fierabracci and Francesca Saura",
year = "2010",
month = "5",
doi = "10.1016/j.diabres.2010.01.018",
language = "English",
volume = "88",
journal = "Diabetes Research and Clinical Practice",
issn = "0168-8227",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes

AU - Fierabracci, Alessandra

AU - Saura, Francesca

PY - 2010/5

Y1 - 2010/5

N2 - A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic (T1D) patient a λUni-Zap cDNA library from human diabetic islets. The significance of the identified autoantigens to the disease pathogenesis remains to be elucidated.

AB - A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic (T1D) patient a λUni-Zap cDNA library from human diabetic islets. The significance of the identified autoantigens to the disease pathogenesis remains to be elucidated.

KW - Autoantibodies

KW - Autoantigens

KW - Human islets cDNA libraries

KW - Type 1 diabetes

UR - http://www.scopus.com/inward/record.url?scp=77952885410&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952885410&partnerID=8YFLogxK

U2 - 10.1016/j.diabres.2010.01.018

DO - 10.1016/j.diabres.2010.01.018

M3 - Article

C2 - 20170975

AN - SCOPUS:77952885410

VL - 88

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

SN - 0168-8227

IS - 2

ER -

Access to Document