Identification of a U7snRNA homologue mapping to the human Xq27.1 region, between the DXS1232 and DXS119 loci

Marina Mostardini, Valentina Appierto, Rossana Pergolizzi, Ileana Zucchi, Steven Mumm, GianLuca Debellis, Luciano Milanesi, Igor B. Rogozin, Ida Biunno

Research output: Contribution to journalArticlepeer-review

Abstract

To contribute to the identification and analysis of novel genes, we undertook the study of a cosmid clone in the Xq27 region of human DNA. The cloned fragment was previously observed to have a high number of evolutionarily conserved sequences. In this genomic stretch of DNA we have identified sequence homologous to the U7 RNA gene including its potential regulatory elements. This paper describes the genomic organisation of this gene and its mapping to the Xq27.1 genomic sub-interval between the DXS1232 and DXS119 loci.

Original languageEnglish
Pages (from-to)221-224
Number of pages4
JournalGene
Volume187
Issue number2
DOIs
Publication statusPublished - Mar 18 1997

Keywords

  • Histone-encoding genes
  • Human X chromosome
  • Minor small nuclear ribonucleoprotein
  • Nucleotide sequence
  • RNA 3' processing

ASJC Scopus subject areas

  • Genetics

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