TY - JOUR
T1 - Identification of common carp innate immune genes with whole-genome sequencing and RNA-Seq data.
AU - Zhang, Yanju
AU - Stupka, Elia
AU - Henkel, Christiaan V.
AU - Jansen, Hans J.
AU - Spaink, Herman P.
AU - Verbeek, Fons J.
PY - 2011
Y1 - 2011
N2 - The common carp is a candidate model system for immunology research. Using next-generation sequencing technology, we have generated a huge amount of sequence reads from the carp genome and transcriptome. Currently, our aim is to identify carp genes involved in the development of the innate immune response, particularly TIR domain-containing genes, from a preliminary genome assembly. To achieve this, we developed a comprehensive gene identification pipeline. This analysis allowed us to estimate that the carp has 39 TIR domain-containing transcript isoforms and genes.
AB - The common carp is a candidate model system for immunology research. Using next-generation sequencing technology, we have generated a huge amount of sequence reads from the carp genome and transcriptome. Currently, our aim is to identify carp genes involved in the development of the innate immune response, particularly TIR domain-containing genes, from a preliminary genome assembly. To achieve this, we developed a comprehensive gene identification pipeline. This analysis allowed us to estimate that the carp has 39 TIR domain-containing transcript isoforms and genes.
UR - http://www.scopus.com/inward/record.url?scp=84862883151&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84862883151&partnerID=8YFLogxK
M3 - Article
C2 - 21908900
AN - SCOPUS:84862883151
VL - 8
SP - 169
JO - Journal of integrative bioinformatics
JF - Journal of integrative bioinformatics
SN - 1613-4516
IS - 2
ER -